Tumor Markers Flashcards
1
Q
Alkaline phosphatase
A
mets to bone or liver
paget disease of bone
seminoma (placental ALP)
2
Q
alpha-fetoprotein
A
Hepatocellular carcinoma** hepatoblastoma yolk sac (endodermal sinus) tumor mixed germ cell tumor high with neural tube defects and abdominal wall defects low with Down's syndrome
3
Q
B-hCG
A
hydatiform moles
choriocarcinomas (gestational trophoblastic disease)
testicular tumor (yup guys make this stuff too)
mixed germ cell tumor
4
Q
CA15-3/CA27-29
A
Breast Cancer
5
Q
CA19-9
A
pancreatic adenocarcinoma
6
Q
CA125
A
ovarian cancer
7
Q
calcitonin
A
medullary thyroid carcinoma
8
Q
CEA
A
colorectal** andpancreatic cancers
gastric, breast, medullary thyroid cancers
non-specific
9
Q
chromogranin
A
neuroendocrine tumors
carcinoid
10
Q
PSA
A
prostate cancer
also high in BPH and prostatitis