Tumor Markers Flashcards

1
Q

Alkaline phosphatase

A

mets to bone or liver
paget disease of bone
seminoma (placental ALP)

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2
Q

alpha-fetoprotein

A
Hepatocellular carcinoma**
hepatoblastoma
yolk sac (endodermal sinus) tumor
mixed germ cell tumor
high with neural tube defects and abdominal wall defects
low with Down's syndrome
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3
Q

B-hCG

A

hydatiform moles
choriocarcinomas (gestational trophoblastic disease)
testicular tumor (yup guys make this stuff too)
mixed germ cell tumor

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4
Q

CA15-3/CA27-29

A

Breast Cancer

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5
Q

CA19-9

A

pancreatic adenocarcinoma

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6
Q

CA125

A

ovarian cancer

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7
Q

calcitonin

A

medullary thyroid carcinoma

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8
Q

CEA

A

colorectal** andpancreatic cancers
gastric, breast, medullary thyroid cancers
non-specific

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9
Q

chromogranin

A

neuroendocrine tumors

carcinoid

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10
Q

PSA

A

prostate cancer

also high in BPH and prostatitis

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