Cytochrome P-450 Interactions Flashcards

1
Q

Chronic Alcohol Use

A

Inducer

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2
Q

St. John’s Wort

A

Inducer

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3
Q

Phenytoin

A

Inducer

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4
Q

Phenobarbital

A

Inducer

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5
Q

Nevirapine

A

Inducer

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6
Q

Rifampin

A

Inducer

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7
Q

Griseofulvin

A

Inducer

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8
Q

Carbamazepine

A

Inducer

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9
Q

Modafinil

A

Inducer

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10
Q

Cyclophosphamide

A

Inducer

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11
Q

Green Vegetables (spinach)

A

Inducer

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12
Q

Acute alcohol abuse

A

Inhibitor

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13
Q

Ritonavir (protease inhibitor)

A

Inhibitor

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14
Q

Amiodarone

A

Inhibitor

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15
Q

Cimetidine

A

Inhibitor

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16
Q

NSAIDS

A

Inhibitor

17
Q

Ketocanazole (azole antifungal)

A

Inhibitor

18
Q

Sulfonamides

A

Inhibitor

19
Q

Isoniazid

A

Inhibitor

20
Q

Grapefruit Juice

A

Inhibitor

21
Q

Quinidine

A

Inhibitor

22
Q

Macrolides (except azithromycin)

A

Inhibitor

23
Q

Ompreazole

A

Inhibitor

24
Q

Gingko

A

Inhibitor

25
Q

Vitamin E

A

Inhibitor

26
Q

thyroid hormone

A

Inhibitor

27
Q

SSRIs

A

Inhibitor

28
Q

Inducers do what to Warfarin?

A

decrease effect

29
Q

Inhibitors do what to Warfarin?

A

increase effect