Cytokines Flashcards

1
Q

IL1

A

osteoclast activating factor
fever, acute inflammation
adhesion molecules expression
recruit WBC

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2
Q

IL6

A

fever

acute phase proteins to enhance phagocytosis

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3
Q

IL8

A

neutrophils

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4
Q

IL12

A
Th1 activation (to get macrophages/cytotoxic T cells)
NK cells
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5
Q

TNF-alpa

A

septic shock

cachexia in maligancy

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6
Q

IL2

A

T cell activation

NK cell

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7
Q

IL3

A

stimulate bone marrow stem cells

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8
Q

Interferon gamma

A

stimulates macrophages

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9
Q

IL4

A
TH2
class switching to IgE
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10
Q

IL5

A

class switching to IgA

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11
Q

IL10

A

attenuate immune response

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