ToRCHeS Infections

Question 1

Toxoplasma gondii

Answer 1

Cat feces
asymptomatic in mom
Neonate –> chorioretinitis + hydrocephalus + intracranial calcifications; blueberry muffin rash

Question 2

Rubella

Answer 2

respiratory droplets
Mom –> rash, lymphadenopathy, arthritis
Neonate –> PDA/pulmonary artery hypoplasia + cataracts + deafness; blueberry muffin rash

Question 3

CMV

Answer 3

sex; organ transplant
Mom –> mono like Sx or no Sx
Neonate –> hearing loss, seizures, petechial rash, preiventricular calcifications, blueberry muffin rash, chorioretinitis

Question 4

HIV

Answer 4

sex; needles
Mom–> depends on CD4 count
Neonates –> recurrent infections, chronic diarrhea

Question 5

HSV 2

Answer 5

skin/mucous membrane contact
mom–> herpetic lesions
Neonates –> encephalitis, herpetic (vesticular lesions)

Question 6

Syphilis

Answer 6

sex
Mom –> chancre (primary) disseminate rash (secondary)
Neonate –> still birth, hydrops fetalis
if alive –> facial abnormalities (notched teeth, saddle nose, short maxilla), saber shins, CN VIII deafness