Tumor markers Flashcards
1
Q
Alkaline phosphatase
A
matastases to bone or liver, paget disease of bone, seminoma (placental ALP)
2
Q
alpha-feroprotein
A
hepatocellular carcinoma, hepatoblastoma, yolk sac, mixed germ cell tumor. High levels in pregnancy –> NTD or abdominal wall defects. Low levers associated with down syndrome
3
Q
B-hcg
A
hydatidiform moles and choriocarcinomas, testicular cancer, mixed germ cell tumor
4
Q
CA 15-3/ CA 27-29
A
breast cancer
5
Q
CA 19-9
A
pancreatic adenocarcinoma
6
Q
CA-125
A
ovarian cancer
7
Q
calcitonin
A
medullary thyroid carcinoma
8
Q
CEA
A
carcinoEmbryonic Antigen. Nonspecific. Also seen in colorectal pancreatic cancers
9
Q
Chromogranin
A
neuroendocrine tumors/carcinoid
10
Q
PSA
A
prostate-specific antigen. prostate cancer.
