P450 Inhibitor, Inducer, or Substrate Flashcards
1
Q
Where are P450 enzymes located?
A
Liver…and small intestine
2
Q
Chronic Alcohol use
A
Inducer
3
Q
OCPs
A
Substrates
4
Q
Macrolides
A
Inhibitor (except azithromycin)
5
Q
Quinidine
A
Inhibitor
6
Q
St. John’s Wart
A
Inducer
7
Q
Phenytoin
A
Inducer
8
Q
Theophylline
A
Substrate
9
Q
Acute Alcohol Use
A
Inhibitor
10
Q
Ritonavir
A
Inhibitor
11
Q
Phenobarbital
A
Inducer
12
Q
Warfarin
A
Substrate
13
Q
Amiodarone
A
Inhibitor
14
Q
Cimetidine
A
Inhibitor
15
Q
Nevirapine
A
Inducer
16
Q
Ketoconazole
A
Inhibitor
17
Q
Sulfonamides
A
Inhibitor
18
Q
Izoniazid
A
Inhibitor
19
Q
Rifampin
A
Inducer
20
Q
Griseofulvin
A
Inducer
21
Q
Grapefruit juice
A
Inhibitor
22
Q
Carbamazepine
A
Inducer
23
Q
Barbituates
A
Inducer
24
Q
Antiepileptics
A
Substrates
