Tumor Markers

Question 0

What is the neoplasm associated with tumor marker alfa-Fetoprotein?

Answer 0

Hepatocellular ca
Hepatoblastoma
Yolk sac (Endodermal Sinus) tumor
Testicular ca
Mixed germ cell tumor (co-secreted with beta-hCG)

Question 1

What is the neoplasm associated with tumor marker alkaline phosphatase?

Answer 1

Metastases to bone, liver
Paget dx of bone
Seminoma (placental ALP)

Question 2

What is the neoplasm associated with tumor marker beta-hCG?

Answer 2

Hydatidiform Moles
Choriocarcinoma (Gestational Trophoblastic dx)
Testicular ca
Normal in pregnancy

Question 3

What is the neoplasm associated with tumor marker CA-15-3/CA-27-29?

Answer 3

Breast ca

Question 4

What is the neoplasm associated with tumor marker CA-19-9?

Answer 4

Pancreatic adenocarcinoma

Question 5

What is the neoplasm associated with tumor marker CA-125?

Answer 5

Ovarian cancer

Question 6

What is the neoplasm associated with tumor marker calcitonin?

Answer 6

Medullary thyroid ca

Question 7

What is the neoplasm associated with tumor marker CEA (CarcinoEmbryonic Antigen)?

Answer 7

Nonspecific
Colorectal ca
Pancreatic ca
Gastric ca
Breast ca
Medullary thyroid ca

Question 8

What is the neoplasm associated with tumor marker PSA?

Answer 8

Follow prostate adenocarcinoma

BPH

Question 9

What is the neoplasm associated with tumor marker S-100?

Answer 9

Neural crest origin;
Melanoma
Neural tumors
Schwannomas
Langerhans cell histiocytosis

Question 10

What is the neoplasm associated with tumor marker TRAP (Tartrate-Resistant Acid Phosphate)

Answer 10

Hairy cell Leukemia - a B-cell neoplasm