Oncogenes

Question 0

What is the neoplasm associated with gene bcl2

and its product?

Answer 0

Follicular and undifferentiated lymphomas

Anti apoptotic molecule

Question 1

What is the neoplasm associated with gene BCR-ABL

and its product?

Answer 1

CML
ALL
Tyrosin kinase

Question 2

What is the neoplasm associated with gene BRAF

and its product?

Answer 2

Melanoma

Serine/threonine kinase

Question 3

What is the neoplasm associated with gene c-kit

and its product?

Answer 3

Gastrointestinal stromal tumor
Cytokine receptor (for stem cell factor)

Question 4

What is the neoplasm associated with gene c-myc

and its product?

Answer 4

Burkitt lymphoma

Transcription factor

Question 5

What is the neoplasm associated with gene HER2/neu (c-erbB2)
and its product?

Answer 5

Breast ca
Ovary ca
Gastric ca
Tyrosine kinase

Question 6

What is the neoplasm associated with gene L-myc

and its product?

Answer 6

Lung tumor

Transcription factor

Question 7

What is the neoplasm associated with gene N-myc

and its product?

Answer 7

Neuroblastoma

Transcription factor

Question 8

What is the neoplasm associated with gene ras

and its product?

Answer 8

Colon ca
Lung ca
Pancreatic ca
GTPase

Question 9

What is the neoplasm associated with gene ret

and its product?

Answer 9

MEN 2A
MEN 2B
Tyrosine kinase