Tumor Markers Flashcards

1
Q

CA 19-9

A

liver/biliary/pancreas (pancreatic adenocarcinoma)

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2
Q

CA 15-3, CA 27-29

A

breast cancer

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3
Q

CA 125

A

ovarian cancer

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4
Q

HER2/Neu

A

breast and gastric

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5
Q

AFP

A

hepatocellular, yolk sac, mixed germ cell tumors, ataxia-telangiectasia, neural tube defects

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6
Q

hCGbeta

A

Hydatidiform moles and Choriocarcinomas (Gestational trophoblastic disease), testicular cancer, mixed germ cell

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7
Q

S100

A

melanoma

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8
Q

PSA

A

prostate

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9
Q

calcitonin

A

medullary thyroid (alone and in MEN2A, 2B) calci2nin

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10
Q

CEA

A

colorectal/pancreas; nonspecific

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11
Q

chromogranin

A

neuroendocrine tumors

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12
Q

alkaline phosphatase

A

mets to bone or liver, Paget disease, seminoma

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13
Q

LDH

A

testicular germ cell tumor, ovarian dysgerminoma, others

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