Tumor Markers Flashcards
1
Q
CA 19-9
A
liver/biliary/pancreas (pancreatic adenocarcinoma)
2
Q
CA 15-3, CA 27-29
A
breast cancer
3
Q
CA 125
A
ovarian cancer
4
Q
HER2/Neu
A
breast and gastric
5
Q
AFP
A
hepatocellular, yolk sac, mixed germ cell tumors, ataxia-telangiectasia, neural tube defects
6
Q
hCGbeta
A
Hydatidiform moles and Choriocarcinomas (Gestational trophoblastic disease), testicular cancer, mixed germ cell
7
Q
S100
A
melanoma
8
Q
PSA
A
prostate
9
Q
calcitonin
A
medullary thyroid (alone and in MEN2A, 2B) calci2nin
10
Q
CEA
A
colorectal/pancreas; nonspecific
11
Q
chromogranin
A
neuroendocrine tumors
12
Q
alkaline phosphatase
A
mets to bone or liver, Paget disease, seminoma
13
Q
LDH
A
testicular germ cell tumor, ovarian dysgerminoma, others