Translocations in Cancer Flashcards

1
Q

t(8;14) c-myc and heavy-chain Ig

A

Burkitt lymphoma

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2
Q

t(14;18) heavy chain Ig and BCL-2

A

Follicular lymphoma

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3
Q

t(11;14) cyclin D1 and heavy chain Ig

A

Mantle cell lymphoma

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4
Q

t(11;18)

A

marginal zone lymphoma

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5
Q

t(9;22) - worst prognosis, t(12;21) -better prognosis

A

ALL

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6
Q

t(15;17)

A

AML (specifically APML > PML/RARA)

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7
Q

t(9;22), BCR-ABL

A

CML

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