Translocations in Cancer Flashcards
1
Q
t(8;14) c-myc and heavy-chain Ig
A
Burkitt lymphoma
2
Q
t(14;18) heavy chain Ig and BCL-2
A
Follicular lymphoma
3
Q
t(11;14) cyclin D1 and heavy chain Ig
A
Mantle cell lymphoma
4
Q
t(11;18)
A
marginal zone lymphoma
5
Q
t(9;22) - worst prognosis, t(12;21) -better prognosis
A
ALL
6
Q
t(15;17)
A
AML (specifically APML > PML/RARA)
7
Q
t(9;22), BCR-ABL
A
CML