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Board Review > Oncogenes > Flashcards

Oncogenes Flashcards

1
Q

ALK

A

receptor TK; lung adenoCA

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2
Q

HER2/Neu

A

receptor TK; breast and gastric CA

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3
Q

RET

A

REceptor Tyrosine kinase; MEN 2A and 2B, medullary and papillary thyroid CA, pheochromocytoma

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4
Q

BCR-ABL

A

non-receptor TK; CML, ALL

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5
Q

JAK2

A

non-receptor TK; myeloproliferative neoplasms

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6
Q

BRAF

A

serine/threonine kinase; melanoma, non-Hodgkin lymphoma, papillary thyroid CA, HCL

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7
Q

c-KIT

A

CytoKIne receptor; GIST, mastocytosis

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8
Q

c-MYC

A

TF; Burkitt

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9
Q

MYCL1

A

TF; Lung cancer

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10
Q

MYCN (N-myc)

A

TF; Neuroblastoma

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11
Q

KRAS

A

RAS GTPase; colorectal, lung, pancreatic cancers

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12
Q

BCL-2

A

antiapoptotic molecule; follicular and DLBCL

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Board Review (9 decks)

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