Antibodies Flashcards
anti-postsynaptic ACh receptor
Myasthenia gravis
anti-presynaptic voltage-gated calcium channel
LEMS
antiphospholipid
anti-beta2 glycoprotein 1, anticardiolipin
SLE
ANA (nonspecific often a/w), anticardiolipin, anti-dsDNA, anti-Smith
antihistone
drug induced lupus
anti-U1 RNP
mixed CT disease
RA
RF (IgM antibody against IgG), anti-CCP (more specific)
anti-Ro/SSA, anti-La/SSB
Sjogren
anti-Scl70 (anti-DNA topoisomerase I)
scleroderma (diffuse)
anticentromere
CREST
anti-synthetase (anti-Jo1), anti-SRP, anti-helicase (anti-Mi-2)
polymyositis, dermatomyositis
antimitochondrial
primary biliary cholangitis
anti-smooth muscle, anti-liver/kidney microsomal-1
autoimmune hepatitis
MPO-ANCA/p-ANCA
microscopic polyangiitis, eosinophilic granulomatosis w/ polyangiitis, UC, primary sclerosing cholangiitis
PR3-ANCA/c-ANCA
granulomatosis w/ polyangiitis