Antibodies Flashcards

1
Q

anti-postsynaptic ACh receptor

A

Myasthenia gravis

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2
Q

anti-presynaptic voltage-gated calcium channel

A

LEMS

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3
Q

antiphospholipid

A

anti-beta2 glycoprotein 1, anticardiolipin

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4
Q

SLE

A

ANA (nonspecific often a/w), anticardiolipin, anti-dsDNA, anti-Smith

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5
Q

antihistone

A

drug induced lupus

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6
Q

anti-U1 RNP

A

mixed CT disease

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7
Q

RA

A

RF (IgM antibody against IgG), anti-CCP (more specific)

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8
Q

anti-Ro/SSA, anti-La/SSB

A

Sjogren

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9
Q

anti-Scl70 (anti-DNA topoisomerase I)

A

scleroderma (diffuse)

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10
Q

anticentromere

A

CREST

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11
Q

anti-synthetase (anti-Jo1), anti-SRP, anti-helicase (anti-Mi-2)

A

polymyositis, dermatomyositis

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12
Q

antimitochondrial

A

primary biliary cholangitis

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13
Q

anti-smooth muscle, anti-liver/kidney microsomal-1

A

autoimmune hepatitis

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14
Q

MPO-ANCA/p-ANCA

A

microscopic polyangiitis, eosinophilic granulomatosis w/ polyangiitis, UC, primary sclerosing cholangiitis

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15
Q

PR3-ANCA/c-ANCA

A

granulomatosis w/ polyangiitis

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16
Q

anti-phospholipase A2 receptor

A

primary membranous nephropathy

17
Q

anti-hemidesmosome

A

bullous pemphigoid

18
Q

anti-desmoglein (anti-desmosome)

A

pemphigus vulgaris

19
Q

antithyroglobulin, antithyroid peroxidase

A

Hashimoto thyroiditis

20
Q

anti-TSH receptor

A

Graves

21
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase (TTG), IgA and IgG deamidated gliadin peptide

A

Celiac

22
Q

anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies

A

T1DM

23
Q

antiparietal cell, anti-IF

A

pernicious anemia

24
Q

anti-GBM

A

Goodpasture