Treponema pallidum Flashcards

1
Q

gram staining

A

gram -

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2
Q

appearance, shape and arrangement

A

corkscrew spiral

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3
Q

mobility

A

motile

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4
Q

spore forming

A

non-spore forming

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5
Q

does it love oxygen

A

microaerophilic

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6
Q

disease it cause

A

syphilis

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7
Q

transmission route of syphilis

A

direct contact of mucous membrane (eg sexual intercourse)
transplacental
blood transfusion

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8
Q

primary syphilis

A

painless spores (genitalia, cervix, anal and oral regions)
enlargement of regional lymph nodes

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9
Q

secondary syphilis

A

healed primary lesion (still present)
maculopapular rash (eg palm and face)
fever
malaise

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10
Q

latent syphilis

A

no visible signs or symptoms but continued infection

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11
Q

tertiary syphilis

A

neurosyphilis (loss of axons and myelin)
cardiovascular syphilis (necrosis, loss of elastic fibers)

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12
Q

congenital syphilis

A

maculopapular rash
anemia
thrombocytopenia
liver failure

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13
Q

pathogenesis

A

remains unclear

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14
Q

treatment

A

penicillin
doxycycline (if allergic)

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