Salmonella Flashcards
1
Q
Salmonella
A
Fascultative, motile, non-spore forming
2
Q
Pathogetic to human
A
Serovar Typhi (O9,12) causes enteric fever
Gastroenteritis
3
Q
Enteric fever
A
Fever, yelliw green diarrhea
Bacteremia
Rose spots l, enlarged liver and spleen
GI perforation leads to GI hemorrhage
4
Q
Pathophysiology
A
S typhi survives through passage through stomach and reach intestines. Invades and destroys human colonic mucosa.
Invade intestinal M cells and enter submucosa, engulfed by macrophages
S typhi multiply in macrophage iin lymph nodes and induce apoptosis
Lead to bloodstream and cause enteric fever
5
Q
Treatment
A
Ciprofloxacin
Cephalosporins
Azithromycin
Fluid replenish
