Neisseria meningitis Flashcards

1
Q

gram staining

A

gram -

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2
Q

shape, appearance and arrangement

A

spiral-shaped, diplococci

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3
Q

mobility

A

non-motile

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4
Q

spore forming

A

non-spore forming

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5
Q

does it like oxygen?

A

aerobic

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6
Q

what enzyme does it produce

A

oxidase

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7
Q

transmission route

A

inhalation of respiratory droplets

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8
Q

antibiotics

A

penicillin and cephalosporins

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9
Q

pathogenesis

A
  1. Neisseria meningitis attach to the cell by outer membrane proteins and pili
  2. multiply in the cytoplasm and escape to submucosa
  3. meningococal capsule allows it to evade phagocytosis and enters the bloodstream and then meninges
  4. after CNS invasion, an intense subarachnoid space inflammatory response
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