Treatments Flashcards
Management of NSTEMI/unstable angina low risk (GRACE score)
Aspirin
Fondaparinux
Ticagrelor if low bleeding risk, clopidegrol if high bleeding risk
Angina treatment
All should receive:
aspirin +statin
GTN
1st line:
- bblocker (atenolol, bisoprolol)
- CCB (amlodopine, diltiazem)
2nd line: Long acting nitrates (Isosorbide mononitrate) K ATP channel activatir (nicorandil) ACEI (dec bp) Ivabradine (HCN channel blocker)
Stemi treatment
Aspirin
- PCI within 120 mins (assuming they’ve come in no longer since 12hrs since MI)
- prasugrel
- unfractioned heparin + glycoprotein
PCI not available:
- Fibrinolysis + antithrombin
- ticagrelor following procedure
- consider PCI for ongoing myo ischaemia/ cardiogenic shock
COPD acute treatment
I SOAP Ipratropium (sama) Salbutamol (nebulised) Oxygen (24-28%, keep saO2 between 88%-92%) Amoxicillin (/doxy/clarithomycin) Prednisolone oral (/hydro IV)
Aminophyline IV (if no response) Non invasive ventillation + docapram IV Consider intubated assisted ventilation if pH< 7.6
How to induce remission in crohns
1st. Monotherapy glucorticoids (prednisolone etc)
En considered in kids
2nd. + azathioprine/mercatopurine to induce remission (check tmpt activity before)
Severe: infliximab/ infliximab + ICS
How to treat acute MI
Morphine (IV) + anti emetic Oxygen (if hypoxic) Nitrates (if ongoing discomfort) Aspirin LMWH (dalteparin) (anticoag) Clopidogrel/ ticagrelor (antiplatelet) Bblocker
H. Pylori treatment
Omeprazole, amoixicillin, clarithomycin/metronidazole
Penicillin allregic:
Omeprazole + clarithomycin+ metronidazole
Gallstones treatment
None if asymptomatic (80%)
If symptomatic:
Laparoscopic cholecystectomy or bile salt acids eg. ursodeoxycholic acid (for smaller stones)
Cholangitis treatment
Emergency ERCP
IV fluids, analgesia, broad spectrum antibiotics
Surgery if ercp fails
Cholecystitis treatment
Acute: nil by mouth,
NSAIDs/opiates,
IV antibiotics (cephlasporin/tazobactam + metronidazole in v ill)
Laparoscopic cholecystectomy
Treatment of hypertension
Examples of Ace: lisinopril Arb: losartan Calcium channel blocker: amlodipine Thiazide like diuretic (d): bendroflumethiazide
Tb treatment
RIPE for 2 months
RI for a further 4 months
Rifampicin
Isonazid
Pyrazinamide
Ethmabutol
(Also negative pressure rooms and N-95 masks)
Tb treatment side effects
Isoniazide- numbness in fingertips/feet
(Im-so-numb-azid)
Ethambutamol- difficulty recognising colours (eye- thambutol)
Rifampicin- orange/red tears/urine
Pyrazinamide- liver toxicity
High risk unstable angina/NSTEMI
aspirin
PCI
Parasugrel/ticagrelor
Unfractioned heparin
COPD treatment for someone w no asthmatic features
1) saba/sama (salbut. / ipatropium)
2) + lABA + LAMA
3) + ICS