principles Flashcards

1
Q

at what stage during CPR should one check the persons pulse to determine return of effective heartbeat

A

when the casualty makes purposeful movement. CPR should not be interrupted otherwise

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2
Q

what describes disordered growth (cells)

A

dysplasia

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3
Q

what word describes cells that grow in the absence of a normal stimulus

A

neoplasia

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4
Q

what genes stimulate normal cell growth

A

proto-oncogenes

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5
Q

what describes an enzyme with a co-factor

A

holoenzyme

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6
Q

what is a nonsense mutation

A

a change in a base which results in a premature stop codon

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7
Q

what is a missense mutation

A

a change in one base which results in a different amino acid being coded for

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8
Q

what is the rate limiting enzyme for gluconeogenesis

A

fructose 1,6 biphosphate

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9
Q

what is the rate limiting enzyme for lipogenesis

A

glycogen phosphorylase

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10
Q

which antibody is responsible for foetal immune protection

A

IgG

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11
Q

which antibody is responsible for neonatal immune protection

A

IgA

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12
Q

what is C-MYC mutation associated with

A

Burkitts lymphoma

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13
Q

CA-125 tumour marker is associated with…

A

ovarian cancer

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14
Q

which HPV is associated with cervical cancer

A

16 and 18

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15
Q

which of the following is protective against breast cancer?
a) late menopause
b) hormone therapy
C) breastfeeding

A

C) breast feeding

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16
Q

benign neoplasm of squamous cell epithelium called?

A

papilloma

17
Q

benign neoplasm smooth muscle

A

leiomyoma

18
Q

what does “sarcoma” describe

A

malignant neoplasm of mesenchymal (connective tissye)

19
Q

where are MHC class II molecules found?

A

found on the cell membrane of macrophages

20
Q

what type of hypersensitivity reaction is sarcoidosis

A

type IV

21
Q

Oxidation is

A

Loss of electrons

22
Q

Reduction is

A

Gain of electrons

23
Q

Oxidising agent

A

Increases the charge of the OTHER element therefore gains electrons (oxidising agent is reduced)

24
Q

A reducing agent

A

Dec charge of OTHER element therefore loses electrons itself.

THE MOLECULE THAT LOSES ELECTRONS
(Reducing agent is oxidised)

25
Q

Pyruvate + NADH + H+ > lactate + NAD+
A) What is the reducing agent
B) What is the oxidising agent

A

NADH as it loses an electron

Pyruvate

26
Q

If delta H (change in enthalpy) is negative, what does that mean for the reaction

A

It is exothermic

27
Q

what does entropy mean (delta s)

A

Level of disorder/chaos

28
Q

If delta G is negative it indicates
Exergonic or enedergonic?
Spontaneous or not?

A

(Catabolic reaction)

Exergonic

Spontaneous

29
Q

If delta G is positive?
Exergonic/endergonic
Spontaneous/not

A

Anabolic reaction
Endergonic
NOT spontaneous

30
Q

Staph aures result on agar plate?

A

Golden/complete haemolysis/ beta haemolysis

31
Q

What type of joint is the sternoclavicular joint?

A

Hinge type

32
Q

What type of joint is elbow joint

A

Saddle type

33
Q

Example of pivot joint

A

Joint between 1st and 2nd vertebrae

34
Q

Example of primary cartilaginous joint

A

Intervertebral disc

35
Q

Example of secondary cartilaginous joint

A

Pubic symphysis

36
Q

Bifurcation of the trachea, what vertebral level

A

T4/5

37
Q

Male nipple anatomical landmarkb

A

4th rib

38
Q

Fundus of stomach has … epithelium

A

Seceretory

39
Q

Which complex does not pump protons through resp chain

A

Complex II