random II

Question 1

antibiotics that inc risk of c.difficile

Answer 1

4 Cs

Clindamycin, cephlosporins (cefuroxime) , co-amoxiclav, ciprofloxacin (quinolones)

Question 2

What does a positive HBsAG indicate

Answer 2

Evidence of infection of hep b

Question 3

What does a positive HBeAg indicate

Answer 3

High viral replication/ infectivity (hep b)

Question 4

What does a positive anti-HBs indicate (surface antibody)

Answer 4

Shows immunity in vaccinated
indicates clearance of infection
(Hep b)

Question 5

Anti- HBe positive indication

Answer 5

Clearance if eAg/ reduced viral replication

Hep b

Question 6

Anti- HBc (core antibody) positive indicates…

Answer 6

Previously infected patient only. (Not positive in vaccinated)
(Hep b)

Question 7

What does HBV DNA PCR diagnose

Answer 7

Level of virulence (hbv)

Question 8

What does positive HCV IgG indicate

Answer 8

Exposure to hep c virus at some point

Question 9

What does HCV RNA indicate

Answer 9

Active infection (detected by PCR)

Question 10

How to induce remission crohns

Answer 10

1st. Monotherapy glucorticoids (prednisolone etc)
En considered in kids

2nd. + azathioprine/mercatopurine to induce remission (check tmpt activity before)

Severe: infliximab/ infliximab + ICS

Question 11

most common lung cancer

Answer 11

Adenocarcinoma

Question 12

What is a positive ama-m2 suggestive of

Answer 12

Primary billiry cirrhosis

autoimmune hepatitis

Question 13

What type of tumour can cause horners syndrome

Answer 13

Pancoast tumor. (A tumor in apex of the lung. Can cause horners by compressing sympathetic chain resulting in droopy eye)

Question 14

How to figure out CURB65

+ what is it used for

Answer 14

Confusion (1)
Urea =/> 7 (1)
Resp >30 (1)
Bp <90s < 60 (1) 
=/> 65 years. (1)
Asseses severity in those with community aquired pneumonia
0= home treatment
1/2= consider hospital referral
3-5= urgent hospital admission

Question 15

Immunocomprimised patient - what pneumonia

Treated with

Answer 15

PCP
(Pneumocystis jiroveci pneumonia)
High dose co-trimaxole

Question 16

Painless obstructive jaundice, old
Diagnosis?
1st line investigation?

Answer 16

Pancreatic cancer, also shows up as double duct on imaging

Abdominal us
Then CT and ERCP to relieve patient. (Stent)

Question 17

What are cancers are the following tumour markers elevated in
a- fetprotein
CEA (carcinoembryonic antigen)
Ca-125
PSA

Answer 17

• Heptocellular carcinomas
• colorectal cancer
• ovarian cancer
• prostate