Treatment of VTE Flashcards
State VTE treatment dose for Enoxaparin in Complicated patient
LMWH e.g. enoxaparin 1mg/kg BD
State enoxaparin dose in uncomplicated PATIENT with low risk of VTE occurrence
1.5mg/kg OD
minimum 5/7 and until oral anticoagulation established
Renal impairment – see SPC
If LMWH contraindicated due to degree of renal impairment or if high bleeding risk - UFH infusion adjusted to APTTr
State oral anticoagulant used in VTE treatment
3/12 and review
Warfarin – dose adjusted according to INR Or DOAC (NOACs) e.g. rivaroxaban, apixaban, edoxaban, dabigatran – check dose in BNF Immediate onset of affect therefore no need for LMWH (except edoxaban)
State other VTE treatment
Thrombolysis
Usually only for acute massive PE
Bleeding risk outweighed by prognosis of condition
Embolectomy
Reversal agents for Anticoagulants
Protamine Full reversal UFH, some reports of partial LMWH reversal Vitamin K Reversal agent for warfarin Idarucizumab Reversal agent for dabigatran andexanet alfa Apixaban or rivaroxaban (direct factor 10a inhibitors
Mechanical prophylaxis of VTE
Anti-embolism stockings
Calf pumps “IPCC”
Geko device
IVC filter