side effects of medications Flashcards
list the common side effects of All Statins
Asthenia; constipation; diarrhoea; dizziness; flatulence; gastrointestinal discomfort; headache; myalgia; nausea; sleep disorders; thrombocytopenia
List the uncommon side effects of All Statins
Alopecia; hepatic disorders; memory loss; pancreatitis; paraesthesia; sexual dysfunction; skin reactions; vomiting
State the Rare or very rare side effects of All Statins
Myopathy; peripheral neuropathy; tendinopathy
State the side effects of Atorvastatin
Common or very common
Epistaxis; hyperglycaemia; hypersensitivity; joint disorders; laryngeal pain; muscle complaints; nasopharyngitis; pain
Uncommon
Appetite decreased; burping; chest pain; fever; hypoglycaemia; malaise; numbness; peripheral oedema; taste altered; tinnitus; vision disorders; weight increased
Rare or very rare
Angioedema; gynaecomastia; hearing loss; severe cutaneous adverse reactions (SCARs)
State the side effects of cephalosporin eg Ceftriaxone
Common or very common
Abdominal pain; diarrhoea; dizziness; eosinophilia; headache; leucopenia; nausea; neutropenia; pseudomembranous enterocolitis; skin reactions; thrombocytopenia; vomiting; vulvovaginal candidiasis
Uncommon
Anaphylactic reaction; angioedema
Rare or very rare
Agranulocytosis; haemolytic anaemia; nephritis tubulointerstitial (reversible); severe cutaneous adverse reactions (SCARs)
state the side effects of Ceftriaxone
Uncommon
Anaemia; coagulation disorder; fungal infection
Rare or very rare
Bronchospasm; glycosuria; haematuria; oedema
Frequency not known
Antibiotic associated colitis; cholelithiasis; hypersensitivity; nephrolithiasis; oral disorders; pancreatitis; seizure; vertigo
State the side effects of Doxycycline
Common or very common
Dyspnoea; hypotension; peripheral oedema; tachycardia
Uncommon
Gastrointestinal discomfort
Rare or very rare
Antibiotic associated colitis; anxiety; arthralgia; flushing; intracranial pressure increased with papilloedema; Jarisch-Herxheimer reaction; myalgia; photoonycholysis; severe cutaneous adverse reactions (SCARs); skin hyperpigmentation (long term use); tinnitus; vision disorders
State the side effects of tetracyclines eg doxycycline
Common or very common
Angioedema; diarrhoea; headache; Henoch-Schönlein purpura; hypersensitivity; nausea; pericarditis; photosensitivity reaction; skin reactions; systemic lupus erythematosus exacerbated; vomiting
Rare or very rare
Appetite decreased; discolouration of thyroid gland; dysphagia; eosinophilia; fontanelle bulging (in infants); gastrointestinal disorders; haemolytic anaemia; hepatic disorders; idiopathic intracranial hypertension; increased risk of infection; neutropenia; oral disorders; pancreatitis; pseudomembranous enterocolitis; Stevens-Johnson syndrome; thrombocytopenia
Frequency not known
Dizziness; tooth discolouration
state the side effects of ethambutol
Common or very common
Hyperuricaemia; nerve disorders; visual impairment
Rare or very rare
Nephritis tubulointerstitial
Frequency not known
Alveolitis allergic; appetite decreased; asthenia; confusion; dizziness; eosinophilia; fever; flatulence; gastrointestinal discomfort; gout; hallucination; headache; jaundice; leucopenia; nausea; nephrotoxicity; neutropenia; photosensitive lichenoid eruption; sensation abnormal; severe cutaneous adverse reactions (SCARs); skin reactions; taste metallic; thrombocytopenia; tremor; vomiting
State the side effects of fentanyl
Common or very common
With parenteral use
apnoea; hypertension; hypotension; movement disorders; muscle rigidity; post procedural complications; respiratory disorders; vascular pain; visual impairment
With sublingual use
asthenia (in adults); dyspnoea (in adults); oral disorders (in adults)
With transdermal use
anxiety; appetite decreased; asthenia; depression; diarrhoea; dyspnoea; gastrointestinal discomfort; hypertension; insomnia; malaise; muscle complaints; peripheral oedema; sensation abnormal; temperature sensation altered; tremor
Uncommon
With parenteral use
airway complication of anaesthesia; chills; hiccups; hypothermia
State the side effects of Fluoxetine
Common or very common
Chills; feeling abnormal; postmenopausal haemorrhage; uterine disorder; vasodilation; vision blurred
Uncommon
Cold sweat; dysphagia; dyspnoea; hypotension; mood altered; muscle twitching; self-injurious behaviour; temperature sensation altered; thinking abnormal
Rare or very rare
Buccoglossal syndrome; leucopenia; neutropenia; oesophageal pain; pharyngitis; respiratory disorders; serum sickness; speech disorder; vasculitis
Frequency not known
Bone fracture
State the side effects of Gabapentin
Common or very common
Anxiety; appetite abnormal; arthralgia; asthenia; behaviour abnormal; confusion; constipation; cough; depression; diarrhoea; dizziness; drowsiness; dry mouth; dysarthria; dyspnoea; emotional lability; fever; flatulence; gait abnormal; gastrointestinal discomfort; headache; hypertension; increased risk of infection; insomnia; leucopenia; malaise; memory loss; movement disorders; muscle complaints; nausea; nystagmus; oedema; pain; reflexes abnormal; sensation abnormal; sexual dysfunction; skin reactions; thinking abnormal; tooth disorder; tremor; vasodilation; vertigo; visual impairment; vomiting
Uncommon
Cognitive impairment; dysphagia; palpitations
Rare or very rare
Respiratory depression
Frequency not known
Acute kidney injury; alopecia; angioedema; breast enlargement; drug use disorders; gynaecomastia; hallucination; hepatic disorders; hyponatraemia; pancreatitis; rhabdomyolysis; severe cutaneous adverse reactions (SCARs); suicidal behaviours; thrombocytopenia; tinnitus; urinary incontinence; withdrawal syndrome
State the side effects of Isoniazid
Uncommon
Hepatic disorders
Rare or very rare
Severe cutaneous adverse reactions (SCARs)
Frequency not known
Agranulocytosis; alopecia; anaemia; aplastic anaemia; eosinophilia; fever; gynaecomastia; haemolytic anaemia; hyperglycaemia; lupus-like syndrome; nerve disorders; optic atrophy; pancreatitis; pellagra; psychosis; seizure; skin reactions; thrombocytopenia; vasculitis
State the side effects of metronidazole
Common or very common
With intravenous use
dry mouth; myalgia; nausea; oral disorders; taste metallic; vomiting
With topical use
skin reactions
With vaginal use
pelvic discomfort; vulvovaginal candidiasis; vulvovaginal disorders
Uncommon
With intravenous use
asthenia; headache; leucopenia (with long term or intensive therapy)
With vaginal use
menstrual cycle irregularities; vaginal haemorrhage
Rare or very rare
With intravenous use
agranulocytosis; angioedema; appetite decreased; ataxia; cerebellar syndrome; confusion; diarrhoea; dizziness; drowsiness; encephalopathy; epigastric pain; epileptiform seizure (with long term or intensive therapy); flushing; hallucination; hepatic disorders; meningitis aseptic; mucositis; nerve disorders; neutropenia; pancreatitis; pancytopenia; peripheral neuropathy (with long term or intensive therapy); psychotic disorder; seizure; severe cutaneous adverse reactions (SCARs); skin reactions; thrombocytopenia; urine dark; vision disorders
With oral use
agranulocytosis; ataxia; cerebellar syndrome; confusion; dizziness; drowsiness; encephalopathy; flushing; hallucination; headache; hepatic disorders; myalgia; neutropenia; pancreatitis; pancytopenia; psychotic disorder; seizure; skin reactions; thrombocytopenia; urine dark; vision disorders
With rectal use
agranulocytosis; ataxia; cerebellar syndrome; confusion; dizziness; drowsiness; encephalopathy; flushing; hallucination; headache; hepatic disorders; myalgia; neutropenia; pancreatitis; pancytopenia; psychotic disorder; seizure; skin reactions; thrombocytopenia; urine dark; vision disorder
Frequency not known
With intravenous use
depressed mood; gastrointestinal disorder; hearing impairment
With oral use
angioedema; appetite decreased; depressed mood; diarrhoea; epigastric pain; epileptiform seizure (with long term or intensive therapy); gastrointestinal disorder; hearing impairment; leucopenia (with long term or intensive therapy); meningitis aseptic; nausea; nerve disorders; oral disorders; peripheral neuropathy (with long term or intensive therapy); severe cutaneous adverse reactions (SCARs); taste altered; tinnitus; vomiting
With rectal use
angioedema; appetite decreased; depressed mood; diarrhoea; epigastric pain; epileptiform seizure (with long term or intensive therapy); gastrointestinal disorder; hearing impairment; leucopenia (with long term or intensive therapy); meningitis aseptic; nausea; nerve disorders; oral disorders; peripheral neuropathy (with long term or intensive therapy); severe cutaneous adverse reactions (SCARs); taste altered; tinnitus; vomiting
State the side effects of Naltrexone
Common or very common
Abdominal pain; anxiety; appetite abnormal; arthralgia; asthenia; chest pain; chills; constipation; diarrhoea; dizziness; eye disorders; headache; hyperhidrosis; mood altered; myalgia; nausea; palpitations; sexual dysfunction; skin reactions; sleep disorders; tachycardia; thirst; vomiting
Uncommon
Alopecia; confusion; cough; depression; drowsiness; dry mouth; dysphonia; dyspnoea; ear discomfort; eye discomfort; eye swelling; feeling hot; fever; flatulence; flushing; hallucination; hepatic disorders; lymphadenopathy; nasal complaints; oropharyngeal pain; pain; paranoia; peripheral coldness; seborrhoea; sinus disorder; sputum increased; tinnitus; tremor; ulcer; urinary disorders; vertigo; vision disorders; weight changes; yawning
Rare or very rare
Immune thrombocytopenic purpura; rhabdomyolysis; suicidal behaviours
Frequency not known
Withdrawal syndrome
State the side effects of paracetamol
Common or very common
With rectal use
anorectal erythema
Rare or very rare
With intravenous use
hypersensitivity; hypotension; leucopenia; malaise; neutropenia
With rectal use
angioedema; liver injury; severe cutaneous adverse reactions (SCARs); skin reactions
Frequency not known
With intravenous use
flushing; skin reactions; tachycardia
With oral use
agranulocytosis; bronchospasm; hepatic function abnormal; rash; severe cutaneous adverse reactions (SCARs)
With rectal use
agranulocytosis; blood disorder
Overdose
Liver damage and less frequently renal damage can occur following overdose.
Nausea and vomiting, the only early features of poisoning, usually settle within 24 hours. Persistence beyond this time, often associated with the onset of right subcostal pain and tenderness, usually indicates development of hepatic necrosis.
For specific details on the management of poisoning, see Paracetamol, under Emergency treatment of poisoning.
State the side effects of Rifampicin
Common or very common
Nausea; thrombocytopenia; vomiting
Uncommon
Diarrhoea; leucopenia
Frequency not known
Abdominal discomfort; acute kidney injury; adrenal insufficiency; agranulocytosis; appetite decreased; disseminated intravascular coagulation; dyspnoea; eosinophilia; eye disorders; flushing; gastrointestinal disorders; haemolytic anaemia; hepatitis; hypersensitivity; influenza; intracranial haemorrhage; menstrual disorder; muscle weakness; myopathy; oedema; pseudomembranous enterocolitis; red discolouration of body fluids; severe cutaneous adverse reactions (SCARs); shock; skin reactions; sputum discolouration; sweat changes; urine discolouration; vasculitis; wheezing
Specific side-effects
Frequency not known
With intravenous use
bone pain; hyperbilirubinaemia; psychotic disorder
With oral use
psychosis
State the side effects of Tamsulosin
Common or very common
Dizziness; sexual dysfunction
Uncommon
Asthenia; constipation; diarrhoea; headache; nausea; palpitations; postural hypotension; rhinitis; skin reactions; vomiting
Rare or very rare
Angioedema; Stevens-Johnson syndrome; syncope
Frequency not known
Dry mouth; epistaxis; vision disorders
State the side effects of Tramadol Hydrochloride
Common or very common
Fatigue
Uncommon
Postural hypotension
Rare or very rare
Dyspnoea; epileptiform seizure; respiratory disorders; sleep disorders; vision blurred
Frequency not known
Asthma exacerbated; hypoglycaemia
State the side effects of Trimethoprim
Common or very common
Diarrhoea; electrolyte imbalance; fungal overgrowth; headache; nausea; skin reactions; vomiting
Rare or very rare
Agranulocytosis; angioedema; anxiety; appetite decreased; arthralgia; behaviour abnormal; bone marrow disorders; confusion; constipation; cough; depression; dizziness; dyspnoea; eosinophilia; erythema nodosum; fever; haemolysis; haemolytic anaemia; haemorrhage; hallucination; hepatic disorders; hypoglycaemia; lethargy; leucopenia; meningitis aseptic; movement disorders; myalgia; neutropenia; oral disorders; pancreatitis; paraesthesia; peripheral neuritis; photosensitivity reaction; pseudomembranous enterocolitis; renal impairment; seizure; severe cutaneous adverse reactions (SCARs); sleep disorders; syncope; systemic lupus erythematosus (SLE); thrombocytopenia; tinnitus; tremor; uveitis; vasculitis; vertigo; wheezing
Frequency not known
Gastrointestinal disorder; megaloblastic anaemia; methaemoglobinaemia
