side effects of medications Flashcards

1
Q

list the common side effects of All Statins

A

Asthenia; constipation; diarrhoea; dizziness; flatulence; gastrointestinal discomfort; headache; myalgia; nausea; sleep disorders; thrombocytopenia

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2
Q

List the uncommon side effects of All Statins

A

Alopecia; hepatic disorders; memory loss; pancreatitis; paraesthesia; sexual dysfunction; skin reactions; vomiting

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3
Q

State the Rare or very rare side effects of All Statins

A

Myopathy; peripheral neuropathy; tendinopathy

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4
Q

State the side effects of Atorvastatin

A

Common or very common
Epistaxis; hyperglycaemia; hypersensitivity; joint disorders; laryngeal pain; muscle complaints; nasopharyngitis; pain

Uncommon
Appetite decreased; burping; chest pain; fever; hypoglycaemia; malaise; numbness; peripheral oedema; taste altered; tinnitus; vision disorders; weight increased

Rare or very rare
Angioedema; gynaecomastia; hearing loss; severe cutaneous adverse reactions (SCARs)

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5
Q

State the side effects of cephalosporin eg Ceftriaxone

A

Common or very common
Abdominal pain; diarrhoea; dizziness; eosinophilia; headache; leucopenia; nausea; neutropenia; pseudomembranous enterocolitis; skin reactions; thrombocytopenia; vomiting; vulvovaginal candidiasis

Uncommon
Anaphylactic reaction; angioedema

Rare or very rare
Agranulocytosis; haemolytic anaemia; nephritis tubulointerstitial (reversible); severe cutaneous adverse reactions (SCARs)

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6
Q

state the side effects of Ceftriaxone

A

Uncommon
Anaemia; coagulation disorder; fungal infection

Rare or very rare
Bronchospasm; glycosuria; haematuria; oedema

Frequency not known
Antibiotic associated colitis; cholelithiasis; hypersensitivity; nephrolithiasis; oral disorders; pancreatitis; seizure; vertigo

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7
Q

State the side effects of Doxycycline

A

Common or very common
Dyspnoea; hypotension; peripheral oedema; tachycardia

Uncommon
Gastrointestinal discomfort

Rare or very rare
Antibiotic associated colitis; anxiety; arthralgia; flushing; intracranial pressure increased with papilloedema; Jarisch-Herxheimer reaction; myalgia; photoonycholysis; severe cutaneous adverse reactions (SCARs); skin hyperpigmentation (long term use); tinnitus; vision disorders

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8
Q

State the side effects of tetracyclines eg doxycycline

A

Common or very common
Angioedema; diarrhoea; headache; Henoch-Schönlein purpura; hypersensitivity; nausea; pericarditis; photosensitivity reaction; skin reactions; systemic lupus erythematosus exacerbated; vomiting

Rare or very rare
Appetite decreased; discolouration of thyroid gland; dysphagia; eosinophilia; fontanelle bulging (in infants); gastrointestinal disorders; haemolytic anaemia; hepatic disorders; idiopathic intracranial hypertension; increased risk of infection; neutropenia; oral disorders; pancreatitis; pseudomembranous enterocolitis; Stevens-Johnson syndrome; thrombocytopenia

Frequency not known
Dizziness; tooth discolouration

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9
Q

state the side effects of ethambutol

A

Common or very common
Hyperuricaemia; nerve disorders; visual impairment

Rare or very rare
Nephritis tubulointerstitial

Frequency not known
Alveolitis allergic; appetite decreased; asthenia; confusion; dizziness; eosinophilia; fever; flatulence; gastrointestinal discomfort; gout; hallucination; headache; jaundice; leucopenia; nausea; nephrotoxicity; neutropenia; photosensitive lichenoid eruption; sensation abnormal; severe cutaneous adverse reactions (SCARs); skin reactions; taste metallic; thrombocytopenia; tremor; vomiting

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10
Q

State the side effects of fentanyl

A

Common or very common
With parenteral use

apnoea; hypertension; hypotension; movement disorders; muscle rigidity; post procedural complications; respiratory disorders; vascular pain; visual impairment

With sublingual use

asthenia (in adults); dyspnoea (in adults); oral disorders (in adults)

With transdermal use

anxiety; appetite decreased; asthenia; depression; diarrhoea; dyspnoea; gastrointestinal discomfort; hypertension; insomnia; malaise; muscle complaints; peripheral oedema; sensation abnormal; temperature sensation altered; tremor

Uncommon
With parenteral use

airway complication of anaesthesia; chills; hiccups; hypothermia

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11
Q

State the side effects of Fluoxetine

A

Common or very common
Chills; feeling abnormal; postmenopausal haemorrhage; uterine disorder; vasodilation; vision blurred

Uncommon
Cold sweat; dysphagia; dyspnoea; hypotension; mood altered; muscle twitching; self-injurious behaviour; temperature sensation altered; thinking abnormal

Rare or very rare
Buccoglossal syndrome; leucopenia; neutropenia; oesophageal pain; pharyngitis; respiratory disorders; serum sickness; speech disorder; vasculitis

Frequency not known
Bone fracture

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12
Q

State the side effects of Gabapentin

A

Common or very common
Anxiety; appetite abnormal; arthralgia; asthenia; behaviour abnormal; confusion; constipation; cough; depression; diarrhoea; dizziness; drowsiness; dry mouth; dysarthria; dyspnoea; emotional lability; fever; flatulence; gait abnormal; gastrointestinal discomfort; headache; hypertension; increased risk of infection; insomnia; leucopenia; malaise; memory loss; movement disorders; muscle complaints; nausea; nystagmus; oedema; pain; reflexes abnormal; sensation abnormal; sexual dysfunction; skin reactions; thinking abnormal; tooth disorder; tremor; vasodilation; vertigo; visual impairment; vomiting

Uncommon
Cognitive impairment; dysphagia; palpitations

Rare or very rare
Respiratory depression

Frequency not known
Acute kidney injury; alopecia; angioedema; breast enlargement; drug use disorders; gynaecomastia; hallucination; hepatic disorders; hyponatraemia; pancreatitis; rhabdomyolysis; severe cutaneous adverse reactions (SCARs); suicidal behaviours; thrombocytopenia; tinnitus; urinary incontinence; withdrawal syndrome

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13
Q

State the side effects of Isoniazid

A

Uncommon
Hepatic disorders

Rare or very rare
Severe cutaneous adverse reactions (SCARs)

Frequency not known
Agranulocytosis; alopecia; anaemia; aplastic anaemia; eosinophilia; fever; gynaecomastia; haemolytic anaemia; hyperglycaemia; lupus-like syndrome; nerve disorders; optic atrophy; pancreatitis; pellagra; psychosis; seizure; skin reactions; thrombocytopenia; vasculitis

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14
Q

State the side effects of metronidazole

A

Common or very common
With intravenous use

dry mouth; myalgia; nausea; oral disorders; taste metallic; vomiting

With topical use

skin reactions

With vaginal use

pelvic discomfort; vulvovaginal candidiasis; vulvovaginal disorders

Uncommon
With intravenous use

asthenia; headache; leucopenia (with long term or intensive therapy)

With vaginal use

menstrual cycle irregularities; vaginal haemorrhage

Rare or very rare
With intravenous use

agranulocytosis; angioedema; appetite decreased; ataxia; cerebellar syndrome; confusion; diarrhoea; dizziness; drowsiness; encephalopathy; epigastric pain; epileptiform seizure (with long term or intensive therapy); flushing; hallucination; hepatic disorders; meningitis aseptic; mucositis; nerve disorders; neutropenia; pancreatitis; pancytopenia; peripheral neuropathy (with long term or intensive therapy); psychotic disorder; seizure; severe cutaneous adverse reactions (SCARs); skin reactions; thrombocytopenia; urine dark; vision disorders

With oral use

agranulocytosis; ataxia; cerebellar syndrome; confusion; dizziness; drowsiness; encephalopathy; flushing; hallucination; headache; hepatic disorders; myalgia; neutropenia; pancreatitis; pancytopenia; psychotic disorder; seizure; skin reactions; thrombocytopenia; urine dark; vision disorders

With rectal use

agranulocytosis; ataxia; cerebellar syndrome; confusion; dizziness; drowsiness; encephalopathy; flushing; hallucination; headache; hepatic disorders; myalgia; neutropenia; pancreatitis; pancytopenia; psychotic disorder; seizure; skin reactions; thrombocytopenia; urine dark; vision disorder

Frequency not known
With intravenous use

depressed mood; gastrointestinal disorder; hearing impairment

With oral use

angioedema; appetite decreased; depressed mood; diarrhoea; epigastric pain; epileptiform seizure (with long term or intensive therapy); gastrointestinal disorder; hearing impairment; leucopenia (with long term or intensive therapy); meningitis aseptic; nausea; nerve disorders; oral disorders; peripheral neuropathy (with long term or intensive therapy); severe cutaneous adverse reactions (SCARs); taste altered; tinnitus; vomiting

With rectal use

angioedema; appetite decreased; depressed mood; diarrhoea; epigastric pain; epileptiform seizure (with long term or intensive therapy); gastrointestinal disorder; hearing impairment; leucopenia (with long term or intensive therapy); meningitis aseptic; nausea; nerve disorders; oral disorders; peripheral neuropathy (with long term or intensive therapy); severe cutaneous adverse reactions (SCARs); taste altered; tinnitus; vomiting

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15
Q

State the side effects of Naltrexone

A

Common or very common
Abdominal pain; anxiety; appetite abnormal; arthralgia; asthenia; chest pain; chills; constipation; diarrhoea; dizziness; eye disorders; headache; hyperhidrosis; mood altered; myalgia; nausea; palpitations; sexual dysfunction; skin reactions; sleep disorders; tachycardia; thirst; vomiting

Uncommon
Alopecia; confusion; cough; depression; drowsiness; dry mouth; dysphonia; dyspnoea; ear discomfort; eye discomfort; eye swelling; feeling hot; fever; flatulence; flushing; hallucination; hepatic disorders; lymphadenopathy; nasal complaints; oropharyngeal pain; pain; paranoia; peripheral coldness; seborrhoea; sinus disorder; sputum increased; tinnitus; tremor; ulcer; urinary disorders; vertigo; vision disorders; weight changes; yawning

Rare or very rare
Immune thrombocytopenic purpura; rhabdomyolysis; suicidal behaviours

Frequency not known
Withdrawal syndrome

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16
Q

State the side effects of paracetamol

A

Common or very common
With rectal use

anorectal erythema

Rare or very rare
With intravenous use

hypersensitivity; hypotension; leucopenia; malaise; neutropenia

With rectal use

angioedema; liver injury; severe cutaneous adverse reactions (SCARs); skin reactions

Frequency not known
With intravenous use

flushing; skin reactions; tachycardia

With oral use

agranulocytosis; bronchospasm; hepatic function abnormal; rash; severe cutaneous adverse reactions (SCARs)

With rectal use

agranulocytosis; blood disorder

Overdose
Liver damage and less frequently renal damage can occur following overdose.

Nausea and vomiting, the only early features of poisoning, usually settle within 24 hours. Persistence beyond this time, often associated with the onset of right subcostal pain and tenderness, usually indicates development of hepatic necrosis.

For specific details on the management of poisoning, see Paracetamol, under Emergency treatment of poisoning.

17
Q

State the side effects of Rifampicin

A

Common or very common
Nausea; thrombocytopenia; vomiting

Uncommon
Diarrhoea; leucopenia

Frequency not known
Abdominal discomfort; acute kidney injury; adrenal insufficiency; agranulocytosis; appetite decreased; disseminated intravascular coagulation; dyspnoea; eosinophilia; eye disorders; flushing; gastrointestinal disorders; haemolytic anaemia; hepatitis; hypersensitivity; influenza; intracranial haemorrhage; menstrual disorder; muscle weakness; myopathy; oedema; pseudomembranous enterocolitis; red discolouration of body fluids; severe cutaneous adverse reactions (SCARs); shock; skin reactions; sputum discolouration; sweat changes; urine discolouration; vasculitis; wheezing

Specific side-effects
Frequency not known
With intravenous use

bone pain; hyperbilirubinaemia; psychotic disorder

With oral use

psychosis

18
Q

State the side effects of Tamsulosin

A

Common or very common
Dizziness; sexual dysfunction

Uncommon
Asthenia; constipation; diarrhoea; headache; nausea; palpitations; postural hypotension; rhinitis; skin reactions; vomiting

Rare or very rare
Angioedema; Stevens-Johnson syndrome; syncope

Frequency not known
Dry mouth; epistaxis; vision disorders

19
Q

State the side effects of Tramadol Hydrochloride

A

Common or very common
Fatigue

Uncommon
Postural hypotension

Rare or very rare
Dyspnoea; epileptiform seizure; respiratory disorders; sleep disorders; vision blurred

Frequency not known
Asthma exacerbated; hypoglycaemia

20
Q

State the side effects of Trimethoprim

A

Common or very common
Diarrhoea; electrolyte imbalance; fungal overgrowth; headache; nausea; skin reactions; vomiting

Rare or very rare
Agranulocytosis; angioedema; anxiety; appetite decreased; arthralgia; behaviour abnormal; bone marrow disorders; confusion; constipation; cough; depression; dizziness; dyspnoea; eosinophilia; erythema nodosum; fever; haemolysis; haemolytic anaemia; haemorrhage; hallucination; hepatic disorders; hypoglycaemia; lethargy; leucopenia; meningitis aseptic; movement disorders; myalgia; neutropenia; oral disorders; pancreatitis; paraesthesia; peripheral neuritis; photosensitivity reaction; pseudomembranous enterocolitis; renal impairment; seizure; severe cutaneous adverse reactions (SCARs); sleep disorders; syncope; systemic lupus erythematosus (SLE); thrombocytopenia; tinnitus; tremor; uveitis; vasculitis; vertigo; wheezing

Frequency not known
Gastrointestinal disorder; megaloblastic anaemia; methaemoglobinaemia