treatment of psychosis

Question 1

Psychosis

Answer 1

• loss of contact with reality
• distortion of mental capacity
• interferes with capacity to cope

Question 2

Symptoms

Answer 2

• hallucinations
• delusion

Question 3

dopaminergic effect

Answer 3

• overproduction of dopamine
• overstimulation of dopamine receptors

NOTE:

Block dopamine receptor

Question 4

Biochemical considerations

Answer 4

• balance of dopamine and acetylcholine receptor stimulation
• imbalance symptoms
  
  • parkinson-like syndrome
  • acute dystonic reaction
• tardive dyskinesia
  
  • not treatable adverse reaction
  • wil never go away (sucking, smacking of the lips, tounge in and out)

NOTE:

• Dpamine receptor block for a long time super sensitized receptors cause
  *

Question 5

Therapeutic side effects

Answer 5

• sedation
• hypotension
• tachycardia
• photosensitivity (exagerated sun burn)
• decresed seizure threshould (more prone to seizures)
• anticholinergic
  
  • dry mouth, blurry vision, dry eye, constipation, urinary retention

Question 6

aliphatic

Answer 6

• low potency, high sedation
  
  • (uses grams high dose)
• high anticholinergic, low EPS

(2 receptors blocks Dopamine and AcH)

Question 7

piperazine

Answer 7

• high potency low anticholinergic
  
  • Low dose in miligrams
  • 1 receptor block (dopamine receptor)
  • acute dystonic rxn.

Question 8

piperadine

Answer 8

• low potency, high anticholinergic

NOTE:

• high dose
• 2 receptor block EPS Low

Question 9

Butyrophenone

Answer 9

High potency, low anticholinergic

Question 10

Dibenzoxazepine

Answer 10

Clozapine- special use procedure, no tardive dyskinesia

NOTE:

jajor adverse reaction low white blood count

Question 11

therapeutic use

Answer 11

• psychosis
• anti- emetic
• intractable hiccups

NOTE:

• Register patient
• run blood test
• blood test registry
• pharmacy ok
• 7 days supply of medication
• blood test
• 7 days supply of medication

The repeats are FDA approved.