Parkinsonism Drug Theraphy

Question 1

Anticholinergic

Answer 1

• Benztropine (cogentin)
• Biperiden (akineton)
• trihexyphenidyl (artane)

Question 2

antihistamine

(block histamine receptor, treaing a symptom)

Answer 2

Diphenhydramine (benadryl)

(mild anticholinergic properties useful for urinary retention, constipation, dry eyes)

Question 3

dopamine and dopamine agonists

Answer 3

• levadopa (larodopa, L-dopa)
• carbidopa/ Levodpa (sinemet)
• amantadine (symmetrel)
  
  • stimulate dopamine receptor in CNS
• Bromocriptine (parlodel)
• pramipexole (mirpex)
  
  • associated with heart failure
• ropinirole (requip)

Question 4

Dopamine receptor stimulants but not dopamine

Answer 4

• amantadine (symmetrel)
• bromocriptine (parlodel)
• Pramipexole (mirapex)
• ropinirole (requip)

Question 5

Inhibitor of MAO

Answer 5

Selegiline (Eldepryl)

Question 6

anticonvulsants

Answer 6

• carbamazepine (tegretol)
• clonazepam (klonopin)
• diazepam (valium)
• lorazepam (ativan)
• Divalproex (depakote)

Question 7

anticonvulsants

Answer 7

• ethosuximide (zarontin)
• felbamate (felbatol)
• lamotrigine (lamictal)
• fosphenytoin
• gabapentin (neurontin)

Question 8

anticonvulsants

Answer 8

• phenobarbital (luminal)
• phenytoin (dilantin)
• primidone (mysoline)