Central muscle relaxants

Question 1

Central muscle relaxant Pharmacology

Answer 1

• Mechanism of action
  
  • central depressant with selective action for skeletal muscle relaxation
• side effects and adverse reactions
  
  • drowsiness, weakness, mental clouding

Question 2

agents with questionable efficacy

Answer 2

• Probable more effect on sedation than muscle relaxation
• carisoprodol
• chlorzoxazone
• methocarbamol
• orphenadrine

Question 3

agents with probable effectiveness

Answer 3

• Diazepam
  
  • (benzodiazepine GABA receptor)
• Cyclobenzaprine (short term use)
  
  • FDA approved for 14 days
  • anticholinergic
  • drugs of no abuse
• Dantrolene
  
  • Therapeutic use
  • malignant hyperthermia
  • seconday to general anesthetics
  1. all muscles contract which gives off heat and raises the temperature
  • neuroleptic hyperthermia
  • secondaryt o antipsychotic agents
  1. antipsychotic
  2. major tranquilizers
  3. places which has alot of heat (dessert)