Treatment of COPD and Asthma Flashcards

1
Q

What are the 4 long term control medications for asthma?

A
  1. inhaled glucocorticoids
  2. long acting inhaled B2-agonists
  3. leukotriene modifiers
  4. omalizumab (anti-IgE)
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2
Q

what would you use a short acting beta agonist for?

A

relive symptoms and prevention of exercise induce asthma

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3
Q

which disease would you use an anti-cholinergic?

A

COPD but not asthma

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4
Q

What are the names of beta adrenergic agonists?

A

alubterol, terbuteline, salmetrerol, formoterol

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5
Q

what is the mechanism of action of beta adrenergic agonists?

A

they stimulate beta adrenergic receptor and cause bronchodilation of smooth muscle and inhibits the production of respiratory secretions

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6
Q

What are the names of anti-cholinergic?

A

atropine, ipratropium, trotropium

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7
Q

what is the route of anti-cholinergics?

A

inhaled

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8
Q

what is the mechanism of anti-cholinergic?

A

cholinergic receptor inhibitors that cause bronchodilation via smooth muscle relaxation

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9
Q

what is a side effect of inhaled glucocorticoids?

A

oral thrush or decrease in growth

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10
Q

what is a bad thing about LABA?

A

they have a black box warning

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11
Q

What should a LABA always be combined with and why?

A

always combine with inhaled corticosteroid

do this because LABA only causes bronchodilation but is not anti-inflammatory

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12
Q

what is the respirable range of particle size?

A

1-5 micrometer

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13
Q

what does a spacer not eliminate?

A

need to shake canister
timing btw actuation and use
tight facemask seal

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14
Q

Why is a spacer prescribed?

A

because it allows the large particles to settle and small particles to get into lungs. It reduces the need for timing and coordination of the inhaler

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15
Q

What is the first line use for acute asthma episode?

A

albuterol

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16
Q

what is the 1st line maintenance for asthma?

A

inhaled glucocorticoids

17
Q

what is the 1st line adjunct for asthma?

A

LABA

18
Q

What is the most important thing you can do for your patient if you prescribe theophylline?

A

Step down the dose because you want to minimize the dose to control the symptoms

19
Q

What is the best non-pharmacologic management of COPD?

A

smoking cessation, then exercise, then flu vaccine

20
Q

what has the greatest capacity to influence the natural history of COPD?

A

smoking cessation

21
Q

What is the treatment course for a patient with COPD? (GOLD 2)

A
long acting anti-cholinergic
rescue inhaler
stop smoking
exercise
immunizations