Treatment of COPD and Asthma Flashcards
What are the 4 long term control medications for asthma?
- inhaled glucocorticoids
- long acting inhaled B2-agonists
- leukotriene modifiers
- omalizumab (anti-IgE)
what would you use a short acting beta agonist for?
relive symptoms and prevention of exercise induce asthma
which disease would you use an anti-cholinergic?
COPD but not asthma
What are the names of beta adrenergic agonists?
alubterol, terbuteline, salmetrerol, formoterol
what is the mechanism of action of beta adrenergic agonists?
they stimulate beta adrenergic receptor and cause bronchodilation of smooth muscle and inhibits the production of respiratory secretions
What are the names of anti-cholinergic?
atropine, ipratropium, trotropium
what is the route of anti-cholinergics?
inhaled
what is the mechanism of anti-cholinergic?
cholinergic receptor inhibitors that cause bronchodilation via smooth muscle relaxation
what is a side effect of inhaled glucocorticoids?
oral thrush or decrease in growth
what is a bad thing about LABA?
they have a black box warning
What should a LABA always be combined with and why?
always combine with inhaled corticosteroid
do this because LABA only causes bronchodilation but is not anti-inflammatory
what is the respirable range of particle size?
1-5 micrometer
what does a spacer not eliminate?
need to shake canister
timing btw actuation and use
tight facemask seal
Why is a spacer prescribed?
because it allows the large particles to settle and small particles to get into lungs. It reduces the need for timing and coordination of the inhaler
What is the first line use for acute asthma episode?
albuterol
what is the 1st line maintenance for asthma?
inhaled glucocorticoids
what is the 1st line adjunct for asthma?
LABA
What is the most important thing you can do for your patient if you prescribe theophylline?
Step down the dose because you want to minimize the dose to control the symptoms
What is the best non-pharmacologic management of COPD?
smoking cessation, then exercise, then flu vaccine
what has the greatest capacity to influence the natural history of COPD?
smoking cessation
What is the treatment course for a patient with COPD? (GOLD 2)
long acting anti-cholinergic rescue inhaler stop smoking exercise immunizations
