Pathology Flashcards
Which lobe is smoking related emphysema usually worst in?
upper lobe
also around the airways
Where is alpha-1-antitrypsin deficiency worse?
lower lobes and throughout the lobe
What is the classic pathologic finding for respiratory bronchiolitis and desquamative interstitial pneumonia?
brown pigmented macrophages because these are both related to smoking diseases
what is the pathophysiology of diffuse alveolar hemorrhage?
neutrophils get into the septa and damage the capillaries leading to hemorrhage
what is the most common form of fibrotic lung diseases?
usual interstitial pneumonia
Which disease shows fibroblastic foci?
usual interstitial pneumonia
where are honeycomb changes worse with UIP?
lower lobes
what is the pathologic characteristics of NSIP?
uniform fibrosis
What is a pathologic feature of talc embolism?
under polarized light, it lights up like whabam
what is the major cause of a talc embolism?
IV drug use resulting in polarized crystals around vessels
what is the the pathologic feature of pulmonary HTN?
muscular hypertrophy of the pulmonary artery and arterioles
what is keratin pearls indicative of?
squamous cell carcinoma
what are small blue easily crushed cells with scant cytoplasm consistent with?
small cell carcinoma
what type of cancer forms gland like structures?
adenocarcinoma
what are the characteristics of large cell carcinoma?
big cells that don’t look similar