Pulmonary Defense Mechanisms Flashcards
1
Q
what is kartageners syndrome?
A
ciliary disease with abnl dynein arm
combo of situs inversus, chronic sinusitis, and bronchiectasis
2
Q
what is the role of a macrophage in the inflammatory response in the lung?
A
it suppresses the adaptive immune response
3
Q
what is the most common cell in a bronchoalveolar lavage?
A
macrophage (90-95%)
4
Q
what are the major APC cells in the lungs?
A
dendritic cells
5
Q
Where does the primary immune response occur in the lung?
A
lymph node
6
Q
what type of disease has an increased CD4:CD8 ratio?
A
granulomatous disease (beryllium, sarcoid, TB)
