Assessment of V/Q Flashcards

1
Q

What happens in an extreme V/Q (infinity)?

A

all ventilation but no perfusion leading to no gas exchange

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2
Q

what happens when V/Q = 0

A

all perfusion but no ventilation leading to no gas exchange

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3
Q

What is the V/Q ratio in the upper lungs? (not a number but relative of ventilation vs perfusion)

A

High ventilation but underperfusion

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4
Q

What is V/Q ratio in lower lungs?

A

high perfusion under ventilation

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5
Q

What are the measurements for PaO2, PaCO2, SAT, CaO2, and CaCO2 at sea level?

A
PaO2= 104
PaCO2 = 40
SAT = 97.5%
CaO2 = 20.7
CaCO2 = 44
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6
Q

What are the measurements for PaO2, PaCO2, SAT, CaO2, and CaCO2 at Denver?

A
PaO2 = 80
PaCO2 = 35
SAT = 95%
CaO2 = 19
CaCO2 = 42
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7
Q

What are the 5 causes of deadspace?

A
rapid shallow breathing
pulmonary embolism
decreased CO
mechanical ventilation
emphysema
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8
Q

what is the clinical definition of a shunt?

A

1% of CO/ 20 torr A-a

blood passes through capillaries but does not get oxygenated

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9
Q

what do shunt and low V/Q contribute to?

A

arterial hypoxemia

arterial hypercapnia

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10
Q

How can you differentiate between a low V/Q and a shunt?

A

low V/Q responds to increased FI02 like if you put the patient on 100% oxygen the V/Q will normalize sat. A shunt does not respond to increased FIO2

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11
Q

What percentage of tidal volume is dead space?

A

1/3

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12
Q

What is the most commonly used mechanism to estimate V/Q mismatch?

A

Calculation of the A-a gradient

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13
Q

In a perfect V/Q mismatched world, PaO2 would be what?

A

78 mmHg

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14
Q

What does SpO2 pulse oximetry measure?

A

hemoglobin saturation

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15
Q

What are the 2 causes of a normal A-a gradient in hypoxemia?

A

altitude

hypoventilation

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16
Q

What are the 3 causes of increased A-a gradient in hypoxemia?

A

diffusion limitation
low V/Q
Shunt