transportation of carbon dioxide Flashcards
how many ways can the carbon dioxide released from respiring tissues be transported?
There are 3 ways in which the carbon dioxide released can transported
What happens to 5% of the carbon dioxide released?
5% of carbon dioxide remains as carbon dioxide molecules and is dissolved in the blood plasma until it reaches the lungs
what happens to 85% of the carbon dioxide released?
85% of the carbon dioxide diffuses into the erythrocyte and binds with water
this binding is catalysed by carbonic anhydrase
CO2 + H2O –> H2CO3
H2CO3 carbonic acid
carbonic acid - H2CO3 is unstable and therefore immediately breaks down –> HCO3 - + H+
where do the products of carbonic acid dissociation end up?
the HCO3- is carried to the lungs
the H+ ions combine with haemoglobin
this combining of the H+ and haemoglobin:
H+ + Hb –> HHB haemoglobin acid
The H+ ions diffuse into haemoglobin and bind to the haem group forcing the oxygen off the haem group in order to allow the dissociation of te oxygen
What diffuses into the erythrocytes to balance their negative charge?
to balance the negative charge of the erythrocytes, chloride ions diffuse into the erythrocytes as the hydrogen carbonate ions diffuse out
‘chlorine shift’
What happens to 10% of the carbon dioxide?
10% of the carbon dioxide diffuses straight into erythrocyte and combines with haemoglobin
CO2 + Hb –> carbaminohaemoglobin