Transplant

Question 1

Most common cause of mortality 1yr after heart txp

Answer 1

Atherosclerosis

Question 2

Predictors of improved pancreatic allograft function

Answer 2

Donor <45
Donor BMI<30
Short preservation time
Traumatic cause of death

Question 3

Early hepatic artery thrombosis post-txp, timing and complication

Answer 3

days to weeks, primary graft nonfunction, fulminant hepatic failure

Question 4

Late hepatic artery thrombosis post-txp, timing and complication

Answer 4

months, biliary strictures, liver abscesses, recurring bacteremia

Question 5

Initial management of mild hepatic rejection

Answer 5

Pulse dose corticosteroids

Question 6

S/p renal txp with headache, HTN refractory to nicardipine, high peak systolic velocity on US; dx and tx

Answer 6

Transplant renal artery stenosis, Percutaneous transluminal angioplasty (PTA)

Question 7

S/p renal txp with adenopathy despite immunosuppression reduction; dx and tx

Answer 7

Post-transplant lymphoproliferative disorder (PTLD), R-CHOP (rituximab-cyclophosphamide-hydroxydaunorubicin-Oncovin-prednisolone)

Question 8

Dx and tx for cardiac allograft rejection

Answer 8

Biopsies, steroid therapy

Question 9

Most common malignancy s/p transplant

Answer 9

Skin cancer

Question 10

Immunosuppressant that carries high risk of new-onset diabetes after transplantation

Answer 10

Tacrolimus, must be >6wks

Question 11

Pancreatic-peritoneal fistula management

Answer 11

Drainage, TPN, bowel rest, +/- octreotide

Question 12

S/p renal transplant, US shows fluid collection without evidence of hematoma, urinoma or abscess on aspiration; dx and tx

Answer 12

Lymphocele, observe

Question 13

Most common cause of ESRD as an indication fro renal txp

Answer 13

Diabetes

Question 14

Pathology acute txp rejection

Answer 14

Lymphocytic infiltration