Transfusion Medicine--Krafts Flashcards
T/F We are born with antibodies against the blood antigen we do no present
T
these antibodies are (oddly) expressed at birth and present throughout life
In what circumstance do you use whole blood?
massive hemorrhage
When do you use RBC transfusions?
severe anemia
When do you use leukoreduced RBCs?
alloimmunized individuals or those allergic to blood products
Why is some red blood frozen?
very rare blood types
When are granulocytes infused?
severe neutropenia and those with severe and unresponsive infection
When do you give platelets?
thrombocytopenia
not just bleeding, only bleeding due to low platelets
What is in fresh frozen plasma?
everything!
Why do you give albumin?
severe kidney failure, helps retain fluids
When is IvIg necessary?
disease prophylaxis
Forward typing is performed on whose blood?
patient and donor blood–determine antigens present on surface
How is reverse typing done?
taking patient’s own antibodies (serum) and reacting them with reagent red cells (known antigens) to see if there is clumping
When do you do an antibody screen?
only in patients who are exhibiting blood reactions and have multiple blood exposures
What is an antibody screen?
looking for weird antigens
What is a cross-match?
using patient’s serum to see if it reacts with the donor RBCs
