Transcription Flashcards
DNA’s code is copied and taken to the
cytosol
after transcription, mRNA without modification is just a
primary transcript
what will happen to a primary transcript that goes outside the nucleus?
destroyed
process of copying the sequence of one strand of DNA
transcription
key factors of transcription:
[PERT]
Promoter and its key element
- TATA box
Enhancers and Silencers
RNA Polymerase II
Transcription factors
- for recruitment of RNA polymerase
catalyzes the formation of rRNA
Polymerase i
catalyzes the formation of mRNA
Polymerase II
catalyzes the formation of tRNA
Polymerase III
tells the RNA polymerase where to attach and begin transcription
promoter
region on DNA where RNA polymerase must begin the transcription of RNA
promoter
TATA box (hogness box) is located here
promoter
contain information for transcription initiation; major site for controlling of gene expression
promoter
promoters are found before the transcriptional start site, approximately how many nucleotides?
25
true or false. TATA-less promoters cannot control transcription
false
what are the elements of TATA-less promoters
Inr (initiator element)
DPE (downstream promoter element)
found 1 nucleotide before the transcription site
Inr
found 28 or 34+ nucleotides before the transcription site
DPE
TCA (G/C) T (T/C)
Inr
(A/G) G (A/T) CGTG
DPE
forms an apparatus that binds DNA and initiates transcription
transcription factors
activated by signals from outside the cell such as hormones and growth factors
transcription factors
sets the stage for transcription by forming a pocking or RNA polymerase
transcription factors
transcription steps:
[IET]
Initiation
Elongation
Termination
binds to the TATA box and recruits other TFs
TFIID
