Toxicity Side effects Flashcards
When to monitor for Lithium
weekly until stable
—> every 3 months (year 1)
——-> every 6 months
When do you record Lithium serum concentration
12 hours after dose
Signs of Lithium Toxicity
SICK and TREMOR
- nausea
- tremor
- increased weeing/thirst
- headache
What organ is not affected by lithium
Liver
What is the therapeutic range for Digoxin
0.7 to 2
When should Digoxin samples be taken
6 hours after dose
What are the signs of Digoxin toxicity apart from Yellow vision
- sick
- confused
- palpitations
What is a rare syndrome you should not give digoxin with
Wolff-Parkinson-White Syndrome
What can be a sign of bone marrow toxicity when taking methotrexate
Mucositis (inflammation of mouth of gut)
What requires discontinuation of methotrexate
- pulmonary toxicity
- bone marrow supression/neutropenia
- Diarrhoea
- Oral mucositis
What should be monitored in methotrexate
- blood
- renal
- liver
When should Methotrexate monitoring take place
- every 1 to 2 weeks until stable
—-> every 2 to 3 months
What should the monitoring frequency be for Methotrexate when taking Leflunomide
monthly for 12 months
What should be monitored with Warfarin
- FBC
- LFT
- renal
- BP
- thyroid
What are signs of toxicity for Theophylline
SICK and FAST
- Nausea
- tremor
- palpitations
- hyperglycaemia