Essential Information part 2 Flashcards
What antibiotics interacts with Methotrexate and what should happen
- Amoxicillin
- Trimethoprim
(stop methotrexate during course of penicillin)
What is usually injected with Isonazide to prevent something
Pyroxidine (Vit B6)
(to reduce risk of peripheral neuropathy)
What when used with methotrexate long term can lead to B12 deficiency
PPIs
What is a sign of hypoglycaemia that Beta Blockers could mask
Tremor
Why would you use water soluble beta blockers
cant pass BBB and less likely to cause CNS side effects (nightmares)
What is the Mnemonic for water soluble Beta Blockers
‘water CANS’
‘water CANS’
C celiprolol
A atenolol
N nadalol
S sotalol
What electrolyte imbalance can ACEi lead to and what can exacerbate it
Hyperkalaemia
(exacerbated in renal impairment)
What is the maximum dose of simvastatin with amlodipine
Simvastatin 20mg
What class of antimicrobials does Warfarin interact with and what happens due to the interaction
Antifungal ‘AZOLES’
increasing warfarin serum conc (increasing INR)
In which patient groups should Citalopram have a maximum dose of 20mg
- older than 65
- hepatic impairment
What laxative should you avoid in IBS and why
lactulose
(can cause bloating)
Which anti-diabetic drugs can cause life threatening DKA
SGLT2i
What medication should you avoid with Statins and what does it casue
Macrolides (clarith, eyrith)
can cause mypoathy
Which Tuberculosis medication can cause hyperuricaemia and what can it cause
Pyrazinamide
(can manifest as gout)
