ToRCH and more Flashcards
congenital toxoplasmosis: fetal effects
hydrocephalus, intracranial calcifications, chorioretinits. can also lead to seizures, SAB
how is toxoplasmosis treated?
best treatment is prevention- pregnant women should avoid cat litter, gardening, raw meat, and unpasteurized milk
can give sulfadiazine, pyrimethamine, folinic acid
What are the fetal manifestations of rubella? What is the treatment?
blueberry muffin rash, hearing loss, vision changes, CV anomalies, CNS abnormalities, hepatiits. classic triad is PDA or pulmonary artery hypoplasia, cataracts, and deafness
risk of SAB
prevention is key- immunize before attempting to conceive if possible. if contract rubella during pregnancy there is no treatment
What are the fetal manifestations of measles?
incr risk of prematurity, IUGR, and SAB.
high risk of neonatal death if disease transmission occurs
How is measles treated during pregnancy?
mother should be immunized before attempting to conceive
if she gets infection during pregnacy, give immune serum globulin
you can’t vaccinate a pregnant woman becasue the virus is live
What are the fetal manifestations of syphilis?
neonatal anemia, deafness due to CNVIII problems, hepatosplenomegaly, PNA, hepatitis, osteodystrophy, rash followed by hand/foot desquamation. high neonatal mortality
What are the fetal manifestations of CMV?
IUGR, chorioretinits, CNS abnormalities, intellectual disability, vision abnormalities, deafness, seziures, hydrocephalus, hepatosplenomegaly
(First aid just lists hearing loss, seizure, petechial or bluberry muffin rash)
What is the tx for CMV during pregnancy?
no tx during pregnancy, ganciclovir may decr the effects in neonates
What are the risks associated with HSV during pregnancy?
incr prematurity, IUGR, SAB, high risk of neonatal death or CNS abnormalities
What is the treatment for hepatitis B in pregnancy?
maternal vaccination. vaccinatio nof neonate and administration of immune globulin shortly after birth
What are the risks of HIV infection during pregnancy?
HIV infection acquired in utero has a rapid progression to AIDS. Recommend early HIV screen during pregnancy and AZT to decr. risk of vertical transmission
What HIV meds should be avoided during pregnancy?
efavirenz, didanosine, stavudine, and nevirapine
When do we screen for GBS? What is the treatment?
screen at 34-37 wks
tx is beta lactams or clindamycin IV during labor
What is the risk of VZV infection during pregnancy?
-encephalitis, PNA, IUGR, CNS abnormalities, limb abnormalities, blidness, high risk of neonatal death
What is the treatment for VZV in pregnancy?
- varicella immune globulin given to nonimmune mom within 96 hrs of exposure and to neonate if born during active infection
- can’t give vaccine in pregnancy
