OA and some rheumatologic DOs

Question 1

Which kind of arthritis involves the distal interphalangeal joints? What other PE findings are common in this disease?

Answer 1

osteoarthritis. may see bony protuberances in the DIP (Heberden nodes) and PIP (Bouchard nodes) joints

Question 2

What are radiographic findings of OA?

Answer 2

joint space narrowing, subchondral bone sclerosis, subchondral bone cyst formation

Question 3

What are the immune markers found in SLE?

Answer 3

-anti-dsDNA antibodies, false positive RPR, ANA, anti-smith

Question 4

What are the immune markers found in drug induced lupus?

Answer 4

antihistone antibodies

Question 5

What antibodies are found in RA?

Answer 5

-rheumatoid factor, ANA, HLADR4 common

Question 6

What antbodies are found in polymyositis or dermatomyositis?

Answer 6

-Anti-jo-1; ANA

Question 7

What antibodies are found in scleroderma?

Answer 7

anti-scl-70, ANA

Question 8

What antibodies are found in CREST syndrome?

Answer 8

anticentromere antibodies

Question 9

What antibodies are found in mixed CT disease?

Answer 9

anti-RNP (ribonucleoprotein), ANA

Question 10

What antibodies are found in Sjogren syndrome?

Answer 10

anti-Ro (SSA) and anti-la (SSB)