Topical Abx w/ various MOA Flashcards

1
Q

What is the spectrum and MOA for Bacitracin?

A

Spectrum: MSSA, Streptococcus pyogenes. MOA: Non-beta-lactam, interferes with cell wall synthesis.

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2
Q

What is Bacitracin used for?

A

Topical administration for skin conditions like impetigo and eye infections.

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3
Q

What are the common uses for Polymyxin B?

A

Topical administration for skin and eye conditions; often part of triple antibiotic ointments.

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4
Q

Which bacteria does Polymyxin B target?

A

MSSA, Streptococcus pyogenes, Gram-negative bacilli including E.coli, Enterobacter, Klebsiella, Pseudomonas, Shigella

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5
Q

What is Mupirocin’s spectrum of activity and MOA?

A

Spectrum: Gram-positive cocci. MOA: Protein synthesis inhibitor.

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6
Q

How is Mupirocin administered and what does it treat?

A

Topically for skin conditions such as impetigo.

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7
Q

What kind of adverse reactions can all these topical drug classes cause?

A

Localized topical reactions.

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