Topic 8- totipotent stem cells Flashcards
What is a stem cell?
a cell that can divide by mitosis an unlimited number of times
What is differentiation?
Each new cell that is produced when a stem cell divides has the potential to remain a stem cell or to develop into a specialised cell such as a blood cell or a muscle cell
Define potency
ability of stem cells to differentiate into more specialised cell types
What are the 3 types of potency
-Totipotency
-Pluripotency
-Multipotency
Which type of cells can divide and produce any type of body cell?
Totipotent (also known as embryonic)
Where do totipotent stem cells exist for a limited amount of time?
-in early mammalian embryos
- in extra-embryonic cells (the cells that make up the placenta)
The zygote is formed when a sperm cell fertilises an egg cell. What type of cell is this?
Totipotent
What type of cells are the embryonic cells up to the 16-cell stage (morula) of human embryo development?
Totipotent
Describe the process of specialisation
-To begin with, totipotent cells in the embryo are unspecialised
-During development, totipotent cells begin to translate only part of their DNA, which results in cell specialisation
-specialised cells then form tissues (no longer considered unspecialised)
Can cells lose their ability to differentiate later in development?
Yes