Topic 8- totipotent stem cells Flashcards

1
Q

What is a stem cell?

A

a cell that can divide by mitosis an unlimited number of times

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2
Q

What is differentiation?

A

Each new cell that is produced when a stem cell divides has the potential to remain a stem cell or to develop into a specialised cell such as a blood cell or a muscle cell

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3
Q

Define potency

A

ability of stem cells to differentiate into more specialised cell types

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4
Q

What are the 3 types of potency

A

-Totipotency
-Pluripotency
-Multipotency

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5
Q

Which type of cells can divide and produce any type of body cell?

A

Totipotent (also known as embryonic)

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6
Q

Where do totipotent stem cells exist for a limited amount of time?

A

-in early mammalian embryos
- in extra-embryonic cells (the cells that make up the placenta)

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7
Q

The zygote is formed when a sperm cell fertilises an egg cell. What type of cell is this?

A

Totipotent

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8
Q

What type of cells are the embryonic cells up to the 16-cell stage (morula) of human embryo development?

A

Totipotent

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9
Q

Describe the process of specialisation

A

-To begin with, totipotent cells in the embryo are unspecialised
-During development, totipotent cells begin to translate only part of their DNA, which results in cell specialisation
-specialised cells then form tissues (no longer considered unspecialised)

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10
Q

Can cells lose their ability to differentiate later in development?

A

Yes

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