TOPIC 6= CELLULAR METABOLISM Flashcards

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1
Q

METABOLISM?

A

SUM OF ALL CHEM REACTIONS IN AN ORGANISM
ARISES FROM ORDERLY INTERACTION BETWEEN MOLECULES

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2
Q

CATABOLIC PATHWAY?

A

RELEASE ENERGY BY BREAKING COMPLEX INTO SMALLER MOLECULES
EX: CELLULAR RESPIRATION

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3
Q

ANABOLIC PATHWAY?

A

CONSUME ENERGY TO BUILD COMPLEX FROM SMALLER MOLECULES
EX: PROTEIN FROM AA

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4
Q

ENERGY? (3)

A

CAPACITY TO CAUSE CHANGE THAT EXISTS IN MANY FORMS, SOME THAT CAN PREFORM WORK

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5
Q

TYPES OF ENERGY?

A

KINETIC, THERMAL, POTENTIAL, CHEMICAL

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6
Q

1ST LAW OF THERMODYNAMICS?

A

ENERGY CANNOT BE CREATED OR DESTROYED, ONLY CONVERTED TO OTHER FORMS. ENERGY IN UNIVERSE IS CONSTANT

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7
Q

2ND LAW OF THERMODYNAMICS?

A

DURING A TRANSFORMATION SOME ENERGY IS LOST AS HEAT, EACH TRANSFORMATION INCREASES ENTROPY OF UNIVERSE

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8
Q

ENTROPY?

A

MEASURE OF MOLECULAR RANDOMNESS AND DISORDER

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9
Q

TRUE OR FALSE: HEAT IS A DISORDERED FORM OF ENERGY?

A

TRUE

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10
Q

SPONTANEOUS PROCESSES? (3)

A

OCCUR WITH NO ENERGY, CAN HAPPEN QUICKLY OR SLOW, INCREASE ENTROPY

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11
Q

FREE ENERGY?

A

ENERGY THAT CAN DO WORK WHEN TEMP AND PRESSURE ARE UNIFORM, SHOWS WHETHER REACTION IS SPONTANEOUS OR NOT

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12
Q

TRUE OR FALSE: DURING SPONTANEOUS CHANGE FREE ENERGY IS LESS THAN ZERO?

A

TRUE

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13
Q

EXERGONIC REACTION? (4)

A

SPONTANEOUS, NEGATIVE, NET RELEASE OF FE, FE LESS THAN ZERO

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14
Q

ENDOGONIC REACTION? (4)

A

ABSORBS ENERGY, NONSPONTANEOUS, FE GREATER THAN ZERO, POSITITVE

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15
Q

TRUE OR FALSE: METABOLISM IS NEVER AT EQUILIBRIUM?

A

TRUE

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16
Q

WHAT ARE THE TYPES OF WORK CELLS DO?

A

CHEM, MECHAN, TRANSPORT

17
Q

ENERGY COUPLING?

A

USE OF EXERGONIC PROCESSES TO DRIVE ENDOGONIC, USED BY CELLS TO DO WORK

18
Q

ATP HYDROLYSIS? (3)

A

BREAKING OF TERMINAL PHOSPHATE OF ATP RELEASES ENERGY, GOES TO LOWER STATE OF FE, EXERGONIC

19
Q

PHOSPHORLATION?

A

TRANSFERRING PHOSPHATE GROUP TO ANOTHER SUBSTANCE, MAKING A PHOSPHORYLATED INTERMEDIATE

20
Q

ATP REGENERATION?(3)

A

EXERGONIC, SPONTANEOUS, ADDING A PHOSPHATE TO ADP, COMES FROM CATABOLIC REACTION IN THE CELL

21
Q

ACTIVATION ENERGY?

A

ENERGY NEEDED TO START CHEM REACTION

22
Q

STEPS FOR ENZYME BINDING? (5)

A
  1. SUBSTRATES ENTER ACTIVE SITE
  2. HELD IN BY WEAK INTERACTIONS
  3. A.S. LOWERS EA
  4. SUBSTRATES TURN INTO PRODUCTS
  5. PRODUCTS GET RELEASED
23
Q

OTHER WAYS TO LOWER EA?

A

STRAINING SUBSTRATE BONDS, PROVIDING FAVOURABLE MICROENVIROMENT, COVALENTLY BONDING TO SUBSTRATE IN REACTION

24
Q

COMPETITIVE INHIBITOR?

A

BINDS TO ACTIVE SITE SO THE SUBSTRATE CANT

25
Q

NONCOMPETITIVE INHIBITOR?

A

BIND TO ANOTHER PART OF ENZYME SO IT CHANGES SHAPE SO ITS LESS EFFECTIVE

26
Q

ALLOSTERIC REGULATION?

A

EITHER INHIBIT/STIMULATE ENZYME WORKING, BINDS TO PROTEIN AT ONE SITE AND AFFECTS PROTEIN FUNCTION AT ANOTHER ONE

27
Q

COOPERATIVITY?

A

ALLOSTERIC REGULATION THAT CAN AMPLIFY AND INFLUENCE AFFINITY FOR MORE SUBSTRATE

28
Q

FEEDBACK INHIBITION?

A

END PRODUCT OF METABOLIC PATHWAY SHUTS IT DOWN