TOPIC 10= DNA STRUCTURE AND REPLICATION Flashcards
WHO INTRODUCED THE DOUBLE HELIX MODEL FOR DNA?
JAMES WATSON AND FRANCIS CRICK
WHAT WAS GRIFFITHS EXPERIMENT?
INJECTED STRAINS OF BACTERIA INTO MICE TO PROVE DNA HAD GENETIC MATERIAL. BEFORE THAT PPL THOUGHT IT WAS PROTIEN (1928)
WHAT WAS HERSHEY AND CHASES EXPERIMENT?
MORE EVIDENCE THAT DNA IS GENETIC MATERIAL, STUDIED VIRSUS THAT INFECT BACTERIA (1952)
WHAT ARE THE NUCLEOTIDES?
ADENINE, THYMINE, CYTOSINE, GUANINE
WHAT WERE CHARGAFFS RULES?
- DNA COMPOSITION VARIES FROM ONE SPECIES TO ANOTHER
- A=T AND C=G
WHO BUILT THE STRUCTURAL MODEL OF DNA?
MAURICE WILKENS AND ROSALIND FRANKIN, ALLOWED WATSON TO PROVE HIS IDEA
DOES DNA HAVE SUGAR?
NO, LACK OF O SUGAR
WHAT IS EVIDENT IN THE DOUBLE HELIX?
RELATIONSHIP BETWEEN STRUCTURE AND FUNCTION, MAYBE SHOWING POSSIBLE COPYING THING
SEMI CONSERVATIVE MODEL?
ONE OLD AND ONE NEW IN THE REPLICATED DNA
CONSERVATIVE MODEL?
PARENT STRANDS REJOIN
DISPERSIVE MODEL?
EACH STRAND IS MIX OF OLD AND NEW
ORGINS OF REPLICATION?
WHERE REP BEGINS, PROKARYOTES HAVE FEW, EUKARYOTES HAVE THOUSANDS OF THEM
LEADING STRAND? (3)
DNA POLYMERASE MAKES IT, MOVING TOWARDS FORK, 5 TO 3
TELOMERASE?
ENZYME THAT LENGTHENS TELOMERES IN GERM CELL, CAN ALLOW CANCER CELLS TO LIVE LONGER BY DIVIDING MANY TIME
CHROMATIN?
DNA AND PROTEIN
