Topic 30 Flashcards
Describe electrochemical potential
The sum of the electric and Chemical potenitals
Give the Nernst-Equation
- R = Gas Constant*
- T = Temperature*
- F = Faraday Constant*
What is the nernest equation used for
Calculating the Electrochemical potential of an ion
Compare Calculated and Measured resting potentials
Calculated values arent always best:
Cell is not a closed system (As regarded in formula)
Ions are assumed to be perfectly immobile
Dependent on the composition of the membrane
The model considers only one type of ion at a time
What are the ion currents accross a mammalian axon membrane?
Ionic current due to Concentration difference (Ic)
Ionic current due to potential difference (Ip)
Describe the ion currents by Na+
Both Ic and Ip are directed into the cell, concentration of Na+ is still bigger outside.
Sodium must be continually brought back against the differences.
Describe the ion currents by Cl-
Ic = Ip, They compensate eachother
Describe the ion currents by K+
Ic > Ip, there must be a mechanism to return K+ to the cell.
Na/K ions diffuse by…
Passive flow
Describe the Na/K pump
Na+ out of cell / K+ Into the cell
Ratio of 3Na+:2K+
Uses ATP