top meds: 21-25 Flashcards

1
Q

trazodone

A

used to treat major depressive disorder by imroveing mood, appetite, and energy level 9also decreases depression related anxiety and insomnia

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2
Q

trazodone: brand names

A

Desyrel, Desyrel Dividose, Oleptro, Trialodine

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3
Q

trazodone: rleated drugs

A

Sertraline, Hydroxyzine, Lexapro, Lorazepam, Zoloft, Citalopram, Cymbalta

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4
Q

trazodone: therapeutic class

A

SARIs (serotonin receptor antagonists and reuptake inhibitors): increase amount of active serotonin in the CNS by blocking function of seotonin transporter proteins. acts as antagonists to inhibit certain serotonin receptor (5HT2a recpetor), block func of serotonin transporter protein, resuling in higher amount of active serononin in CNS

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5
Q

trazodone: common interactions

A
  • other antidepressants
  • Phenytoin (anticonvulsant)
  • St. John’s Wort
  • Tramadol (opioid analgesic)
  • diuretics, anticoagulants (Warfarin)
  • Migraine Headache Medicines
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6
Q

trazodone: contraindications

A
  • liver, kidney, heart disease
  • recent heart attack
  • bleeding/blood clotting disorder
  • seizures, epilepsy
  • drug addiction, bipolar disorder
  • suicidal thoughts, manic depression
  • narrow-angle glaucoma
  • long QT syndrome
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7
Q

trazodone: dosaging

A
  • 18 and under cannot get it w/o parent consent
  • adults w/ depression (tab form): start @ 150mg/day, can increase by 50mg every 3-4 days
  • inpatient: 600mg/day
  • outpatient: 400 mg/day
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8
Q

trazodone: side effects

A

nausea, diarrhea, drowsiness, blurred vision, weight change, body pain, dry mouth, stuffy nose, change in sexual activity

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9
Q

trazodone: adverse affects

A

flutter/fast heartbeat, short breaths, sudden dizziness, unusual thoughts, brusing, bleeding, low sodium, slurred speech, no coordination, fever, twitching

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10
Q

trazodone: additional info

A
  • can be used on animals
  • affects qualty of sleep
  • encouraged to not take while pregnant
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11
Q

dextroamphetamine/amphetamine

A

used to treat narcolepsy and ADHD by raising bp, bt, and hr

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12
Q

dextroamphetamine/amphetamine: brand names

A

Adderall SR, Mydaysis

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13
Q

dextroamphetamine/amphetamine: related drugs

A

all end in -il, or -all, plus: Xyrem and Sodium oxybate

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14
Q

dextroamphetamine/amphetamine: therapeutic class

A

CNS stimulant: increases level of certain chemicals in the brai nadn increases alertness, attention, enevery and physical avtivity. Indise the presynaptic terminal, amphetamine increases the amounts of monoamine neuroransmitters in the cytosol thru inhibition of VMAT2 (vesicular monomaine transporter) as well as thru disruption of the electrochemical gradients necessary for vesicular transporter function

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15
Q

dextroamphetamine/amphetamine: common interactions

A
  • drugs that increase acid levels in urine
  • drugs that increase sodium
  • serotonergic drugs
  • bp drugs
  • chlorpromazine
  • seixure drugs
  • haloperidol
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16
Q

dextroamphetamine/amphetamine: contraindications

A
  • Galucoma
  • hyperthyroidism
  • feelings of anxiety, tension, or agitation
  • tachycardia
  • pregnacy
    -mania BPD MPD
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17
Q

dextroamphetamine/amphetamine: side effects

A

no eat=weight loss, dry mouth, stomach nausea, dizzy, poop issues, fever, sleep issues

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18
Q

dextroamphetamine/amphetamine: adverse effects

A

chills, cough, liquid poop, fever, joint pain, no eat, sweating, wounds on fingers adn toes, weid skin, parts of the head/face/neck swell

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19
Q

fluticasone

A

used to treat pain, swelling, and itching on skin 9also used for prevention of asthma attacks

20
Q

fluticasone: brand names

A

Flovent HFA, Ticanase, Ticaspray (starts with Ti-, starts w/ Fl- like Fluicasone)

21
Q

fluticasone: related drugs

A

Budesonide, Mometasone, Trimcionlone (all end in -e, 2 end w/ -ne)

22
Q

fluticasone: therapeutic class

A

corticosteroid class: decreases inflammation and slow down activity in immune system

23
Q

fluticasone: common interactions

A
  • HIV protease inhibitors (ex.: Ritonavir & Lopinavir)
  • grapefruit and related citrus items
24
Q

fluticasone: contraindications

A

-formula contains lactose so should avoid if allergic
- hypersensitivity to medication

25
Q

fluticasone: dosaging

A

nothing written on slide
- 3 types: nasal spray, tablet, tropical ointment

26
Q

fluticasone: side effects

A

trouble swallowing, nosebleed, cough, body ache, itchy, hives, fever, nausea

27
Q

fluticasone: adverse effects

A

dysphoria, cough, Pnumonia, oral thrush, Adrenal/growth suppression, bruising, Glaucoma

28
Q

tamsulosin

A

used to treat men w/ symptoms of enlarged prostate or benign prostatic hyperplasia (also used to treat kidney stones and prostatitis)

29
Q

tamulosin: brand names

A

Flomaxtra XL, Contiflo XL, Paramsil MR, Pamsvax XL, Tabphyn MR (flomaxtra is most common, all end with -XL or -ML)

30
Q

tamsulosin: related drugs

A

end in -sin, just like tamsulosin

31
Q

tamsulosin: therapeutic class

A

alpha blockers: blocks smooth muscle receptors in prostate and urethra so muscles in prostate and bladder relax so urine can flow easily

32
Q

tamsulosin: common interactions

A
  • other alpha blocker drugs (prazosin, terazosin), ED or pulmonary hypertension (sildenafil, tadalafil), other meds like azole antifungals, HIV protease inhibitors
  • alcohol or tobacco
33
Q

tamsulosin: contraindications

A
  • hypersensitivity to tamsulosin hydrochloride or other components in drug
34
Q

tamsulosin: dosaging

A

-only for adults w/ BPH: o.4mg capsules P.O, QD. can go up to 0.8 mg QD depending on patient. should take 30 min after meal @ same time every day
- no specific dosage for kidney or liver problems

35
Q

tamsulosin: side effects

A

cough, fever, back pain, painful urination, abnormal ejaculation, congestion, loss of strength, swollen neck glands

36
Q

tamsulosin: adverse effects

A

dizziness, painful/ prolonged erection, sensation of spinning, less sexual drive, nausea, trouble sleeping

37
Q

tamsulosin: additional info

A
  • store in closed container # room temp.
  • taking Flomax can restore urin flow but an cause drop in BP when going from sitting to standing
38
Q

Fluoxetine

A

mainly used for treating depression (also treats mood disorders like OCD, bulimia nervosa, and panic disorder)

39
Q

Fluoxetine: brand names

A

2 has “Prozac”, plus: Sarafrem

40
Q

Fluoxetine: related drugs

A

(all SSRIs) Celexa, cymbalta, lexapro, paxil, zoloft

41
Q

Fluoxetine: therapeutic class

A

SSRI (selective serotonin repurake inhibitor): works by increasing activing of serotonin in brain. they do this by blocking readbsoprtion of serotonin into neurons

42
Q

Fluoxetine: common interactions

A
  • drugs that affect hemostasis can increase risk of gastrointestinal bleeding
  • NSAIDS, aspirin, warfin, etc.
  • amino acids L-dopa, L-tryptophan, anorexiants, anticonvulsants, antidepressants, anxioltics, calcium channel blockers, cyproheptadine, lithium salts, and drugs or alcohol
43
Q

Fluoxetine: contraindications

A
  • use of MAOIs (Monamine Oxidase inhibitors)
  • Linesolid, pimozide, thioridazine, tamoxifen: combo-ing can cause seizures
  • elderly patients for patients 18-24 can have suicidal thoughts
  • pregnacy is risk factor but can still be taken
44
Q

Fluoxetine: dosaging

A

orally: caps, solution, delyed release caps, pulvules
depression:
- adults: 20mg QD, can change over time
- children 8+: 10-20mg QD, children 8-: determined by doctor (DBD)
bulimia nervosa:
- adults:60mg QD
-Children: DBD
OCD:
- adults: 20mg QD
- children 7+: 10mg QD, children 7-: DBD
panic disorder:
- adults: 20mg QD
-children: DBD

45
Q

Fluoxetine: side effects

A

nausea, insomnia, poop issues, anxiety, eat more, headache, funky dreams, sleepiness, seating, flue, bleeding gums, allergic reaction, yawning, low libido, confusion

46
Q

Fluoxetine: adverse effects

A

diabetes, heart arrhythmia, bleeding conditions, seizures, difficulty breath/swallow, fever, tremors, impotence