med term chp. 13 Flashcards
albumin
blood protein that maintains the proper amount of water in the blood
antibody
immunoglobulin produced by lymphocytes to combat specific antigens
antigen
forgein substance that stimulates the production of an antibody
basophil
white blood cell containing granules that stain blue; associated with release of histamine and heparin
bilirubin
orange yellow pignment in bile; formed by the breakdown of hemoglobin
coagulation
blood clotting
differentiation
change in structure and function of a cell as it matures
electrophoresis
method of separating serum proteins by electrical charge
eosinophil
white blood cell containing granules that stain red; associated with allergic reactions
erythrocyte
rbc
erytrhoprotein
hormone secreted by kidneys that stimulate rbc formation
fibrin
protein threads that form the basis of a blood clot
fibrinogen
plasma protein that is converted to fibrin in the clotting process
globulins
plamas proteins; ex.: alpha, beta, gamma
granulocyte
wbc w/ numberous dark staining granules; neutrophil, basophil, and eosinophil
hemoglobin
blood protein containing iron
hemolysis
destruction or breakdown of blood
immune reaction
response of immune system to foreign invasion
plasma
liquid portion of the blood
macrophage
monocyte that migrates from the blood to tissue spaces; a phagocyte
lymphocyte
mononuclear leukocyte that produces antibodies
herapin
anticoagulant found in blood and tissue cells
hematopoietic stem cell
unspecialized cell that gives rise to mature, specialized forms; found in bone marrow
immunoglobulin
protein with antibody activity; ex.: IgG, IgA, IgM, IgD, IgE
neutrophil
wbc contianing granules and formed in bone marrow
plasmapheresis
removal of plasma from the withdrawn blood by centrifuge
platelet (thrombocyte)
small blood granment that collects at sites of injury to begin the clotting process
reticulocyte
immature rbc
serum
plasma minus clottting proteins and cells
anticoagulant
substance that stops blood clotting
coagulophathy
disorder or disease of clottting
cytology
study of cells
erytrhrocytopenia
deficiency of rbc
hematocrit
percentage of rbc in volume of blood
hemoglobinopahty
disorder marked by abnormality in hemoglobin
hemolysis
destruction or breakdown of blood (rbc)
hypochromic
pertaining to a deficiency in color (rbc)
leukocytoPENIA
deficiency of wbc
myeloBLAST
immature bone marrow cell
MORPHology
study of shape (of cells)
neutroPENIA
deficiency of neutrophils
MYELOdysplasia
abnormal formation of bone marrow
MONOcyte
wbc with one large nucleus
PHAGOcyte
cell that eats or swallows bacteria and debris
SIDEROpenia
deficiency of iron
THROMBOCYTOpenia
deficiency of platelets
POLYMORPHOnuclear
pertaining to a wbc with multilobed (shaped) nucleus
erythroblast
immature rbc
leukapheresis
wbc are serpated from other parts of the blood
marcocytosis
abnormal condition of large rbc
microcytosis
abnormal condition of small rbc
monoblast
immature wbc
plasmapheresis
plasma is sperarated from other parts of the blood
plateletpheresis
clotting cells are separated from other parts of the blood
poikilocytosis
abnormal condition of rbc that are irrgularly shaped
spherocytosis
abnormal condition of rounded rbc
immunoGLOBULIN
antibody containing protein in blood
thromboLYTIC therapy
therapy mused to dissolve (breakdown) clots
myelOID
resembling bone marrow cells
granuloCYTOPENIA/ granuloPENIA
deficiency of granulocytes
meutroPHILIA
increase in numbers of neutrophils
thrombOSIS
abnormal condition of clotting
hematoPOIESIS
formation of blood
panCYTOPENIA/ panPENIA
deficiency of all types of blood cells
myeloPOIESIS
formation of bone marrrow cells
hemoSTASIS
stopping or controlling the flow of blood
aplastic anermia
fialure of blood cell production due absence of formation of bone marrow cells
hemocromatosis
excess iron deposits throughout the body
hemolytic anemia
reduction in red cells due to excessive destruction
hemophilia
excessive bleeding caused by hereditary lack of factor VIII or favotr X necessary for blood bclottin
monoculceosis
infectious disease marked by increased numbers of leukocytes and enlarged cervical lymp nodes
pernicious anemia
lack of mature erytrhocytes caused by inablitity to absorb vitamin B12 into the body
polychythemia vera
gernal increase in rbc (erythremia)
purpura
multiple pinpoint hemorrhages and accumulation of blood under the skkin
sickle cell anemia
hereditary condition characterized by abnormal cresent shape of the rbc and by hemolysis
thhalassemia
inherited defect in the ability to produce hemoglobin, usually seen in persons of Mediterranean background
chronic lymphoid leukimia (CLL)
abnormal numbers of relatively mature lymphocytes predominate in the bone marrow, lympth nodes, and spleen
acute myeloid leukemia (AML)
immature tranulocytes are predominate in the bone marrow
chronic myeloid leukemia (CML)
both mature and immature tranulocytes are present in the bone marrow and bloodstream
acute lymphoid leykemia (ALL)
immature lymphocytes predominate in the bone marrow and lymph nodes
dyscrasia
any disease of the blood or bone marrow
ecchymoses
large blue or purplish patches on the skin (bruises)
eosinophilia
increase in numbers of granulocytes associated with allergic conditions
Epstein-Barr virus
causative agent in mononucleosis
iron deficiency anemia
sideropenia is the cause of this condition
multiple myeloma
malignant meoplams of bone marrow
palliative
relieving, but not curing disease
petechiae
tiny purple or red flat spots on the skin as a result of hemorrhages
relapse
disease symptoms and signs reappear
remission
disappearance of signs and symptoms of disease
antiglobulin test
test for the presence of antibodies that coat and damage erythrocytes
bleeding time
time required for blood to stop flowing from a tiny puncture wound
coagulation time
time required for nevous blood to clot in a test tube
compelte blood count
determination of number of blood cells, hemoglobin and hematocrit, and other rbc values
erythrocyte sedimentation rate
speed at which erythrocytes settle out of plasma
hemoglobin test
total amount of hemoglobin in a smaple of peripheral blood
platelet count
number of thrombocytes per cubic milimeter or microliter of blood
rbc count
number of erythrocytes per cubic milimeter or microliter of blood
rbc morphology
microscopic examination of a stained blood smear to determine shape of rbcs
apheresis
separation of blood into component parts and removal of a select portion from the blood
blood transfusion
whole blood or cells are taken from donor and infused into a patient
bone marrow biopsy
microscopic examination of a core of bone marrow reoved with a needle
hematopoietic stem cell transplantation
peripheral stem cells from a donor are administered into a recipient
prothrombin time
test of the ability of blood to clot
wbc count
number of leukocytes per cubic milimeter of blood
wbc differntial
percentages of the difference types of leukocytes in the blood