tooth development Flashcards

1
Q

all body tissues develop from 3 primary embryonic layers, what are they?

A

. ectoderm
. mesoderm
. endoderm

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2
Q

which primary embryonic layer does the enamel develop from?

A

ectoderm

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3
Q

which primary embryonic layer do all parts of the teeth and supporting structure other than the enamel develop from?

A

ectomesenchyme

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4
Q

what is ectomesenchyme derived from?

A

neural crest

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5
Q

what do teeth develop from?

A

tooth germs

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6
Q

what is neural crest tissue referred to?

A

ectomesenchyme

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7
Q

neural crest tissue migrates into what?

A

developing face and jaw

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8
Q

name the 5 stages of tooth development

A

initiation, bus stage, cap stage, bell stage, eruption

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9
Q

what occurs during the initiation stage of tooth development?

A

. oral epithelium proliferates into the ectomesenchymal cells situated below to form a primary epithelial band
. primary epithelial band differentiates into vestibular lamina and dental lamina containing tooth germs

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10
Q

at how many weeks does the primary epithelial band develop?

A

6

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11
Q

at how many weeks does the primary epithelial band differentiate into dental lamina and vestibular lamina?

A

7

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12
Q

what is the function of dental lamina?

A

structure from which tooth is formed

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13
Q

what is the function of vestibular lamina?

A

breaks down to from buccal suculus

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14
Q

when does the bud stage of tooth formation start?

A

8-10 weeks

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15
Q

what occurs during the bud stage of tooth development?

A
  • dental lamina thickens into a bud stage enamel organ

- ectomesenchymal cells condense to form dental papilla

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16
Q

when does the cap stage of tooth formation start?

A

11 weeks

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17
Q

what occurs during the cap stage of tooth development?

A

tooth bud forms a cap over the papilla

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18
Q

the tooth bud is arranged into 3 parts, what are these?

A

enamel organ, detal papilla and dental follicle

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19
Q

at which stage are the internal and external enamel organ epithelium seen for the first time?

A

cap stage

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20
Q

where do the internal and external enamel epithelium meet?

A

cervical loop

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21
Q

when does the bell stage of tooth formation start?

A

14 weeks

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22
Q

what occurs during the bell stage of tooth development?

A

more cell layers differentiate and tooth shape is formed

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23
Q

how many layers are there during the bell sated of tooth development?

24
Q

name the 4 layers present during bell stage of tooth formation

A

stellate reticulum, internal enamel epithelium, external enamel epithelium, stratum intermedium

25
what is the function of the stellate reticulum?
supporting tissue during enamel formation
26
where is the the stratum intermedium?
developing tooth layer between inner epithelium and stellate reticulum
27
the does the dental lamina for the permanent successor tooth appear?
week 12
28
what does the dental lamina of permanent successor tooth appear as?
an extension of the lingual side of dental lamina
29
what occurs during the late bell stage of tooth formation?
crown shape is well defined and enamel and dentin begin to from
30
during the formation of dentin, dental papilla cells adjacent to the internal enamel epithelium differentiate into which cells?
odontoblasts
31
what do odontoblasts do during dentin formation?
lay down dentin matrix which is later mineralised
32
after dentin formation has begun, intra enamel epithelium cells differentiate into what?
ameloblasts
33
what do dormant ectomesenchymal cells from?
tertiary dentin
34
what are the 2 stages of enamel formation?
protein matrix formation and mineralisation
35
name the 4 stages of the ameloblast lifecycle
differentiation, secretion, maturation, regression
36
what occurs during ameloblast differentiation?
. dentin induces IEE cells to differentiate into ameloblast | . ameloblasts elongate, nucleus migrates to basal end
37
what occurs during secretory phase of ameloblast lifecycle ?
. ameloblasts become secretory cells | . they synthesise and secrete enamel matrix proteins
38
what occurs during maturation phase of ameloblast lifecycle ?
. most matrix protein removed | . mineralised content of enamel increased
39
what occurs during protection phase of ameloblast lifecycle ?
. ameloblasts regress to form a protective layer | . form epithelial attatcmnent
40
what is the name for proliferation of epithelial cells located at the cervical loop of the enamel organ in a developing tooth?
henrtwigs epithelial tooth sheath
41
how many layers does henrtwigs epithelial root sheath have?
2
42
what happens to henrtwigs epithelial root sheath once the initial layer of root dentin is formed?
it breaks up
43
what does henrtwigs epithelial root sheath form?
root dentin
44
what do remains the remains of henrtwigs epithelial root sheath remain as?
debris of malassez
45
what may debris of malaise develop into?
cyst
46
how is the cementum formed from mesenchymal cells?
mesenchymal cells from the follicle contact the dentin and differentiate into cementoblasts
47
fibres from PDL are embedded in what structure?
cementum
48
what type is tissue is enamel organ?
epithelium
49
where does enamel organ originate?
ectoderm
50
what is the product of enamel organ?
enamel
51
what type of tissue is dental papilla?
ectomesenchyme
52
where does dental papilla originate?
neural crest
53
what parts of the tooth do dental papilla form?
dentine and pulp
54
what type of tissue is the dental follicle?
ectomesenchyme
55
where does the dental follicle originate?
neural crest
56
what structures does the dental follicle form?
cementum, PDL, alveolar bone
57
name some disorders associated with dental development
hypodontia, supernumerary, gemoiantion, fusion, dentinogenesis imperfecta