tooth development Flashcards

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1
Q

all body tissues develop from 3 primary embryonic layers, what are they?

A

. ectoderm
. mesoderm
. endoderm

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2
Q

which primary embryonic layer does the enamel develop from?

A

ectoderm

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3
Q

which primary embryonic layer do all parts of the teeth and supporting structure other than the enamel develop from?

A

ectomesenchyme

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4
Q

what is ectomesenchyme derived from?

A

neural crest

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5
Q

what do teeth develop from?

A

tooth germs

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6
Q

what is neural crest tissue referred to?

A

ectomesenchyme

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7
Q

neural crest tissue migrates into what?

A

developing face and jaw

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8
Q

name the 5 stages of tooth development

A

initiation, bus stage, cap stage, bell stage, eruption

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9
Q

what occurs during the initiation stage of tooth development?

A

. oral epithelium proliferates into the ectomesenchymal cells situated below to form a primary epithelial band
. primary epithelial band differentiates into vestibular lamina and dental lamina containing tooth germs

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10
Q

at how many weeks does the primary epithelial band develop?

A

6

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11
Q

at how many weeks does the primary epithelial band differentiate into dental lamina and vestibular lamina?

A

7

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12
Q

what is the function of dental lamina?

A

structure from which tooth is formed

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13
Q

what is the function of vestibular lamina?

A

breaks down to from buccal suculus

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14
Q

when does the bud stage of tooth formation start?

A

8-10 weeks

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15
Q

what occurs during the bud stage of tooth development?

A
  • dental lamina thickens into a bud stage enamel organ

- ectomesenchymal cells condense to form dental papilla

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16
Q

when does the cap stage of tooth formation start?

A

11 weeks

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17
Q

what occurs during the cap stage of tooth development?

A

tooth bud forms a cap over the papilla

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18
Q

the tooth bud is arranged into 3 parts, what are these?

A

enamel organ, detal papilla and dental follicle

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19
Q

at which stage are the internal and external enamel organ epithelium seen for the first time?

A

cap stage

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20
Q

where do the internal and external enamel epithelium meet?

A

cervical loop

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21
Q

when does the bell stage of tooth formation start?

A

14 weeks

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22
Q

what occurs during the bell stage of tooth development?

A

more cell layers differentiate and tooth shape is formed

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23
Q

how many layers are there during the bell sated of tooth development?

A

4

24
Q

name the 4 layers present during bell stage of tooth formation

A

stellate reticulum, internal enamel epithelium, external enamel epithelium, stratum intermedium

25
Q

what is the function of the stellate reticulum?

A

supporting tissue during enamel formation

26
Q

where is the the stratum intermedium?

A

developing tooth layer between inner epithelium and stellate reticulum

27
Q

the does the dental lamina for the permanent successor tooth appear?

A

week 12

28
Q

what does the dental lamina of permanent successor tooth appear as?

A

an extension of the lingual side of dental lamina

29
Q

what occurs during the late bell stage of tooth formation?

A

crown shape is well defined and enamel and dentin begin to from

30
Q

during the formation of dentin, dental papilla cells adjacent to the internal enamel epithelium differentiate into which cells?

A

odontoblasts

31
Q

what do odontoblasts do during dentin formation?

A

lay down dentin matrix which is later mineralised

32
Q

after dentin formation has begun, intra enamel epithelium cells differentiate into what?

A

ameloblasts

33
Q

what do dormant ectomesenchymal cells from?

A

tertiary dentin

34
Q

what are the 2 stages of enamel formation?

A

protein matrix formation and mineralisation

35
Q

name the 4 stages of the ameloblast lifecycle

A

differentiation, secretion, maturation, regression

36
Q

what occurs during ameloblast differentiation?

A

. dentin induces IEE cells to differentiate into ameloblast

. ameloblasts elongate, nucleus migrates to basal end

37
Q

what occurs during secretory phase of ameloblast lifecycle ?

A

. ameloblasts become secretory cells

. they synthesise and secrete enamel matrix proteins

38
Q

what occurs during maturation phase of ameloblast lifecycle ?

A

. most matrix protein removed

. mineralised content of enamel increased

39
Q

what occurs during protection phase of ameloblast lifecycle ?

A

. ameloblasts regress to form a protective layer

. form epithelial attatcmnent

40
Q

what is the name for proliferation of epithelial cells located at the cervical loop of the enamel organ in a developing tooth?

A

henrtwigs epithelial tooth sheath

41
Q

how many layers does henrtwigs epithelial root sheath have?

A

2

42
Q

what happens to henrtwigs epithelial root sheath once the initial layer of root dentin is formed?

A

it breaks up

43
Q

what does henrtwigs epithelial root sheath form?

A

root dentin

44
Q

what do remains the remains of henrtwigs epithelial root sheath remain as?

A

debris of malassez

45
Q

what may debris of malaise develop into?

A

cyst

46
Q

how is the cementum formed from mesenchymal cells?

A

mesenchymal cells from the follicle contact the dentin and differentiate into cementoblasts

47
Q

fibres from PDL are embedded in what structure?

A

cementum

48
Q

what type is tissue is enamel organ?

A

epithelium

49
Q

where does enamel organ originate?

A

ectoderm

50
Q

what is the product of enamel organ?

A

enamel

51
Q

what type of tissue is dental papilla?

A

ectomesenchyme

52
Q

where does dental papilla originate?

A

neural crest

53
Q

what parts of the tooth do dental papilla form?

A

dentine and pulp

54
Q

what type of tissue is the dental follicle?

A

ectomesenchyme

55
Q

where does the dental follicle originate?

A

neural crest

56
Q

what structures does the dental follicle form?

A

cementum, PDL, alveolar bone

57
Q

name some disorders associated with dental development

A

hypodontia, supernumerary, gemoiantion, fusion, dentinogenesis imperfecta