TLR Signaling Flashcards

1
Q

TLR1 + TLR2 recognize _____ and produce ________.

A

Triacylated lipoproteins, peptidoglycans, lipopolysaccharides

Inflammatory Cytokines

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2
Q

TLR2 + TLR6 recognize _______ and produce _______.

A

Diacylated lipoproteins

Inflammatory Cytokines

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3
Q

TLR3 recognizes ________ and produces __________.

A

dsRNA, tRNA, siRNA

Inflammatory Cytokines, Type 1 IFN (BOTH)

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4
Q

TLR4 recognizes ________ and produces __________.

A

LPS, Pacitaxel

Inflammatory Cytokines, Type 1 IFN (BOTH)

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5
Q

TLR5 recognizes ________ and produces __________.

A

Flagellin

Inflammatory Cytokines

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6
Q

TLR7 recognizes ________ and produces __________.

A

ssRNA

Inflammatory Cytokines, Type 1 IFN (BOTH)

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7
Q

TLR8 recognizes ________ and produces __________.

A

ssRNA

Inflammatory Cytokines, Type 1 IFN (BOTH)

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8
Q

TLR9 recognizes ________ and produces __________.

A

CpGDNA

Inflammatory Cytokines, Type 1 IFN (BOTH)

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9
Q

TLR10 recognizes ________ and produces __________.

A

Profilin-like proteins

Inflammatory Cytokines

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