TLC - L3 - Hormones Flashcards
What is a hormone?
A substance secreted into the blood by specialized cells in response to a stimulus.
What was the first hormone identified?
Secretin - regulates secretions from intestine.
What is a neurocrine hormone?
Hormone released into synaptic cleft adjacent to where the neurone contacts the target cell.
What are the 4 main groups of hormones?
- Peptide.
- Steroid.
- Tyrozine derivatives.
- Eicosanoids.
What are peptide hormones synthesized from?
Amino acids.
What size are peptide hormones?
Variable.
Give examples of peptide hormones?
- Thyrotropin releasing hormone.
- Gonadotrophin releasing hormone.
What size are glycoprotein peptide hormones?
Large molecules.
Give examples of glycoprotein peptide hormones?
Gonadotrophins from the anterior pituitory:
- Leutenising hormone.
- Follicle stimulating hormone.
Where are steroid hormones synthesized?
- Adrenal cortex.
- Testis.
- Ovary.
- Placenta.
What are adrenalin, noradrenaline, dopamine and the thyroid hormones derived from?
Tyrozine.
What are the thyroid hormones?
- Thyroxine.
- Triodothyronine.
Name some lipid insoluble hormones - do not enter cells?
- Adrenaline.
- Noradrenaline.
- Dopamine.
Are the thyroid hormones lipid soluble?
Yes.
What are the 2 types of eicosanoid messengers?
- Prostaglandins.
- Leukotrienes.