Tissues Flashcards
What is the Study of Tissues called
Histology
4 Main Types of Tissues
Nervous
Epithelial
Muscle
Connective
What are Germ Layers
First types of tissues in embryonic development
What are the 3 Primary Germ Layers
Endoderm
Mesoderm
Ectoderm
What do the 3 Primary Germ Layers have in common
Epithelial Tissue
Defining Characteristics of the Endoderm Germ Layer
GI, Respiratory and Urinary Tissues
Defining Characteristics of the Mesoderm Germ Layer
Most muscle and ALL Connective Tissue
Defining Characteristics of the Ectoderm Germ Layer
Nervous Tissue
What are the 5 Types of Cell Junctions
Tight Adherens Desmosome Hemidesmosome Gap
Define Cell Junctions
The junction and adherence between the plasma membranes of cells
Define Tight Junctions
Transmembrane proteins fuse the outer surface of adjacent cells to prevent the passage of substances into or out of blood and tissues
Where in the body are Tight Junctions found (3)
Stomach
Intestines
Bladder
What does Plaque refer to
Dense protein on inside of cell membrane that is involved in Adherens Junctions
Describe Adherens Junctions
The cells’s plaque is associated with Actin Microfilaments that attach to Cadherin (transmembrane) proteins to form an adhesion belt (that often circumnavigates the entire cell membrane)
What do Adherens Junctions Prevent
Separation of the layers of cells
Analogy for Adherens Junctions
Velcro Strips
Describe Desmosomes
Plaque at specific locations on the inside of the cell membrane attach to Intermediate Filaments (made of Keratin) as well as to the Transmembrane Protein Cadherin
Analogy for Desmosomes
Buttons
Where in the body are Desmosome Junctions found (2)
Epidermis
Cardiac Muscle
How do Hemidesmosomes differ from Desmosomes
Glycoprotein is Integrin instead of Cadherin, which binds to another external membrane protein called Laminin
Function of Hemidesmopsome Junctions
Attach a cell to the basement membrane
Where in the body are Hemidesmosomes found (1)
Between Epidermis and Dermis
Describe Gap Junctions
Tunnel like connections made up of the glycoprotein Connexin
Function of Gap Junctions
Attach adjacent cells together while still allowing communication or the movement of substances (wastes, ions, nutrients, electrical signals etc)
Where in the body are Gap Junctions found
Many places!
Nervous and Muscle Tissue
How do nerve and muscle cells conduct electrical impulses
Via Gap Junctions
Which type of cell junction contains Keratin and Intermediate Filaments
Desmosomes
Which type of cell junction(s) contain Cadherin
Adherens and Desmosomes
Which type of cell junction contains Actin and Microfilaments
Adherens
Which type of cell junction contains Connexin
Gap Junctions
Which type of cell junction contains Integrin
Hemidesmosomes
How are epithelial cells arranged
In layers - single or multiple, depending on area of body
Describe the nerve and blood supply to epithelial tissue
Innervated well but Avascular
4 Key Functions of Epithelial Tissue
Protection
Absorption of nutrients
Excretion of wastes
Secretion of hormones
What are the 3 surfaces of epithelial cells
Apical
Lateral
Basal
Describe the Apical surface of an epithelial cell
Free side that opens up into body cavity or lumen of an organ/vessel
What does Lumen refer to
Cavity space of an organ or vessel
Describe the Lateral surface of an epithelial cell
The side shared with adjacent cells
Where cell junctions are found
Describe the Basal surface of an epithelial cell
The side opposite to the Apical surface
Attaches cell to basement membrane
On which cell surface would cilia or microvilli be found
Apical
What is the Basement Membrane
Layer that attaches epidermis to underlying connective tissue
What is analogous to the Basement Membrane
The layer that connects carpet to the ground
What does the Basement Membrane consist of (2)
Basal Lamina
Reticular Lamina
Which layer of the Basement Membrane is the deepest
Reticular Lamina
What are the 3 Cell Arrangement Types (Epithelium)
Simple
Pseudostratified
Stratified
Describe Simple Epithelium
Single layer
Describe Pseudostratified Epithelium
Single layer but appears multilayered due to projections that give it a stratified look
Describe Stratified Epithelium
Multilayered
Example of place in body where Simple Epithelium are found
Alveolar sacs of the lungs (gas exchange - happens quickly!)
Where in the body are Stratified Epithelium found
Areas that require strength/reinforcement
Areas where a layer of cells may slough off easily and need replacing
What are the 4 Shapes of Epithelial Cells
Squamous
Cuboidal
Columnar
Transitional
Describe Squamous Shaped Cells and their Function
Flat
F: High absorption rate
Ex. Lungs and capillaries
Describe Cuboidal Shaped Cells and their Function
Cube shaped with microvilli
F: Secretion and Absorption
Describe Columnar Shaped Cells and their Function
Column shaped with microvilli
F: Secretion and Absorption
Describe Transitional Shaped Cells and their Function
Flat to Cuboidal shape
F: Allows for distention and stretch
4 General Epithelia Cell Terms
Goblet
Ciliated
Mesothelium
Endothelium
Describe Goblet Cells (3)
Cells that produce and secrete mucus
Modified Columnar Shape
Can be Endocrine or Exocrine