Tissue Nematodes Flashcards
Wuchereria bancrofti causes ____________
filariasis
What are the symptoms of filariasis?
fever
elephantiasis
lymphangitis
cellulitis
Where does immediate hypersensitivity occur in the body if there is filariasis?
Lungs
What happens in immediate hypersensitivity?
Eosinophilia and increased IgE tropical pulmonary eosinophilia
What are the two species of mosquitoes that spread Wuchereria bancrofti?
Anopheles
Culex
What does the infective female mosquito deposit when it bites the human in filariasis?
Larvae of Wuchereria bancrofti
Microfilariae of Wuchreria has a special characteristic?
Circulate in blood at night
What does a mosquito ingest when bites an infected person with wuchereria?
microfilariae
___________ causes filariasis in Malaysia
Brugia malayi
Brugia malayi causes filariasis in _________
Malaysia
Why are the symptoms of elephantiasis produced in filariasis?
Worms in the lymph nodes cause inflammation that eventually obstructs the lymph node.
__________ species are found intracellularly within filarial nematodes
Wolbachia
Wolbachia are rickettsia like bacteria that produces __________ and is thought to play a role in pathogenesis of filarial infections
endotoxin
___________ kills the Wolbachia, resulting in a reduction of microfilaria number and inflammation
Doxycycline
Tropical pulmonary eosinophilia is characterized by what symptoms?
Cough and wheezing, especially at night
Onchocerca volvulus causes ____________
onchocerciasis
Toxocara canis and catis cause _______________
visceral larvae migrans
Toxocara is spread in humans by _______ (animal)
Dog
Explain the spread of toxocara
Worms in dog intestine → Lay eggs → pass in feces → soil gets contaminated → child ingest the soil → eggs hatch into larva → larva dies → granuloma is formed
What are the clinical features of toxocara?
blindness
fever
hepatomegaly
eosinophilia
What are the organs affected by toxocara?
Brain
Eyes
Liver
(Bel in dog’s neck)
Humans are the ________ (definitive/secondary/reservoir/accidental) hosts
accidental
How can we diagnose toxocara?
Detect larvae in tissues
Hypergammaglobulinemia
Eosinophilia
How can we treat toxocara infection?
Albendazole
Mebendazole
It may resolve without treatment