Thyroid Physiology Flashcards
function of thyroid hormone
needed for growth
basal energy metabolism
increases CO
keep conc of cholesterol in blood in check
what happens if you have too little thyroid hormones
failure of body growth, mental retardation
cretinism
extreme hypothyroidism in early life
if pt is hypothyroid what does TSH look like
higher than normal conc
if pt is hyperthyroid what does TSH look like
lower than normal conc
graves
excessive thyroid hormone due to immune system problem
hashimoto
hypothyroidism
also autoimmune
adult onset hypothyroidism looks like
slowing down - tried, decreased appeitite, constipation, cold intolerance, hair loss
presentation of hyperthroidism
palpitations, increase blood colume, emotional instability, heat intolerance
how does thryiod hormone travel in the blood
bound to plasma proteins - TBG. also TTR, albumin, and lipoproteins can all work
iodide trapping
concentrating iodide in the cell
organification
process of binding iodine with the thryoglobulin
what is another name for throxine biding prealbumin
TTR
transthyretin (TTR)
semi-specific thyroid binding hormone, can also transport retinal
thyroglobulin is also know as what
colloid
