Renal Clearance Flashcards
1
Q
renal clearance
A
volume of plasma per unit time from which all the substance has been removed
2
Q
what is the equation for clearance
A
urine flow rate (V) x urine concentration of X / Plasma concentration of X
3
Q
why can you use inulin to measure GFR
A
because it is not secreted or reabsorbed
4
Q
what is the creatinine clearence in patients with a very low GFR
A
severely overestimated
5
Q
What are the variables in the cockcrock-fault formula
A
blood level of creatinine
age
lean body weight
6
Q
What are the variables in the MDRD study
A
serum creatinine
age
race (if you are black or not)
sex
7
Q
how do nephrons change with age?
A
decreases
8
Q
how does hypertension/diabetes affect renal function with age
A
causes a more rapid decline
