Thyroid, parathyroid and adrenals Flashcards

1
Q

Which structure is the only complete cartilage ring in the neck?

A

Cricoid

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2
Q

Why is expansion of the thyroid dangerous?

A

if it expands, it expands posteriorly and crushes the trachea

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3
Q

Papillary cancer

A

Young people, stays local with good prognosis

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4
Q

Follicular cancer

A

Middle aged, spreads to lung and bone, usually good prognosis

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5
Q

Anaplastic cancer

A

Aggressive, very poor prognosis

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6
Q

red flags thyroid cancer

A

Rapid growth, cough, enlarged cervical LNs, tethering of lump to muscle

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7
Q

Treatment thyroid cancer

A

Thyroidectomy
Radioiodine therapy
External beam therapy
Chemotherapy

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8
Q

Why do you make more TSH when thyroid not working

A

Negative feedback - less T3/4 means more TSH made

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9
Q

Blood to thyroid

A

Superior thyroid artery, inferior thyroid artery

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10
Q

Which pouch are the superior parathyroid glands from?

A

Fourth pharyngeal pouch

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11
Q

Which pouch are the inferior parathyroid glands from?

A

Third pharyngeal pouch

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12
Q

Embryology of thyroid

A
  • The thyroglossal duct pushes outwards from the pharyngeal floor
  • It descends to the neck to form the thyroid gland
  • The foramen caecum (midline punctum at junction of middle + posterior thirds of tongue) marks origin
  • Lower end of duct persists to become gland whilst the rest disappears
  • The thyroid gland is enclosed by pre-tracheal fascia which blends with laryngeal fascia so the thyroid moves upwards on swallowing
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13
Q

Malignant thyroids

A

Cancer can erode trachea/oesophagus/carotid sheath = stridor, dysphagia, haemorrhage

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14
Q

When will Horner’s syndrome arise?

A

Invasion of cervical sympathetic chain

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15
Q

Horners sx

A
  • Affects one side of face only
  • Persistently small pupil, differently sized pupils, little/delayed pupil opening, drooping of upper eyelid, elevation of lower eyelid, sunken appearance to eyes, little/no sweating on one side of face
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16
Q

Primary hyperparathyroidism

A

Caused by parathyroid gland adenoma, hyperplasia or carcinoma
Increased PTH, Increased calc and decreased phos

17
Q

Secondary hyperparathyroidism

A

Hypertrophy of glands in response to hypocalcaemia

Increased PTH, decreased calc, increased phosphate

18
Q

Tertiary hyperparathyroidism

A

Parathyroid hyperplasia after longstanding secondary hyperparathyroidism
Increased pTH and increased calc

19
Q

high aldosterone

A

Conn’s syndrome

20
Q

Congenital adrenal hyperplasia

A

21-hydroxylase deficiency

21
Q

Hypocalcaemia causes

A

PTH glands not functioning after surgery

22
Q

Hypocalcaemia sx

A

Paraesthesia, seizures, Chovstek and Trousseau’s sign

23
Q

Hypocalcaemia treatment

A

Supplemental ca2+